Nano-Structured Pyrophosphate Na2CaP2O7 as Catalyst for Selective Synthesis of 1,2-Disubstituted Benzimidazoles in Pure Water

Author(s): Karim Dänoun, Ilham Jioui, Mohamed Bouhrara, Mohamed Zahouily, Abderrahim Solhy, Mustapha Jouiad, Christophe Len, Aziz Fihri.

Journal Name: Current Organic Chemistry

Volume 19 , Issue 21 , 2015

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Abstract:

We report on synthesis of 1,2-disubstituted benzimidazoles in pure water using nano-structured pyrophosphate Na2CaP2O7. Our findings showed that this heterogeneous catalyst exhibited high catalytic activity and high selectivity in the synthesis of 1,2- disubstituted benzimidazoles from direct cyclocondensation of aromatic aldehydes with substituted benzene-1,2-diamine in pure water. The salient benefits of this method rely on various factors namely: a simple procedure, mildness of the reaction conditions, short reaction times, operational simplicity, high chemoselectivity, low cost and recyclability of the catalyst.

Keywords: Green chemistry, heterogeneous catalysis, benzimidazoles, diaminoarene, aldehydes, recyclable catalyst.

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Article Details

VOLUME: 19
ISSUE: 21
Year: 2015
Page: [2132 - 2140]
Pages: 9
DOI: 10.2174/1385272819666150807190728
Price: $58

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