Plant Secondary Metabolites- Potent Inhibitors of Monoamine Oxidase Isoforms
Githa E. Mathew,
Target of monoamine oxidase inhibitions are considered as the treatment of depressive states and
neurodegenerative disorders, including Parkinson’s and Alzheimer’s diseases. Many medicinal chemistry research groups
are actively working in this area for the development of most promising selective MAO inhibitors. Many plant isolates
also showed remarkable MAO inhibition in recent years. The objective of this review is to identify the major MAO
inhibitors secondary metabolites from plants like flavonoids, alkaloids and xanthones class of compounds.
Keywords: Alkaloids, flavonoids, monoamine oxidase inhibitors, xanthones.
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