Unexpected Course of Kabachnik-Fields Reaction in the Microwave Synthesis of Quinoline-Based α-Aminophosphonates

Title: Unexpected Course of Kabachnik-Fields Reaction in the Microwave Synthesis of Quinoline-Based α-Aminophosphonates

Volume: 6 Issue: 1

Author(s): Marina Juribasic, Laura Stella, Zeljko Marinic, Marijana Vinkovic, Pietro Traldi and Ljerka Tusek-Bozic

Affiliation:

Keywords: α-Aminophosphonate, quinoline, microwave-assisted reaction, Kabachnik-Fields reaction

Abstract: The course of Kabachnik-Fields reaction in the synthesis of 3-substituted quinoline-based α-aminophosphonates under microwave irradiation has been investigated. Some unexpected monoester hydrogen phosphonate derivatives, obtained along with diethyl phosphonates by reaction of quinoline-3-carboxaldehyde and aniline as well as 3- aminoquinoline and benzaldehyde, respectively, with diethyl phosphite, have been analyzed and discussed.

Cite this article as:

Juribasic Marina, Stella Laura, Marinic Zeljko, Vinkovic Marijana, Traldi Pietro and Tusek-Bozic Ljerka, Unexpected Course of Kabachnik-Fields Reaction in the Microwave Synthesis of Quinoline-Based α-Aminophosphonates, Letters in Organic Chemistry 2009; 6 (1) . https://dx.doi.org/10.2174/157017809787003142