Abstract
The process of drug discovery and development requires enormous resources and time, with increasing cost for new drug development. Molecular imaging techniques have tremendous potential for improving the efficiency of drug screening, assessing the pharmacokinetics of new drugs, and evaluating drug effects. Appropriate application of molecular imaging to drug discovery and development can markedly reduce costs and the time required for new drug development. This review focuses on the contributions of molecular imaging for drug discovery and development, particularly drug screening, pharmacokinetic, preclinical and clinical drug evaluation, and for personalized and lesionalized medicine.
Keywords: Drug discovery and development process, molecular imaging, drug screening, pharmacokinetic study, preclinical and clinical study, personalized medicine, lesionalized medicine, efficiency of drug screening, drug effects, pharmacokinetic, preclinical and clinical drug evaluation, combinational chemistry technologies, optical imaging, imaging, magnetic resonance imaging (MRI), ultrasound imaging and computed tomography (CT)
Current Pharmaceutical Biotechnology
Title: Applications of Molecular Imaging in Drug Discovery and Development Process
Volume: 12 Issue: 4
Author(s): Byeong-Cheol Ahn
Affiliation:
Keywords: Drug discovery and development process, molecular imaging, drug screening, pharmacokinetic study, preclinical and clinical study, personalized medicine, lesionalized medicine, efficiency of drug screening, drug effects, pharmacokinetic, preclinical and clinical drug evaluation, combinational chemistry technologies, optical imaging, imaging, magnetic resonance imaging (MRI), ultrasound imaging and computed tomography (CT)
Abstract: The process of drug discovery and development requires enormous resources and time, with increasing cost for new drug development. Molecular imaging techniques have tremendous potential for improving the efficiency of drug screening, assessing the pharmacokinetics of new drugs, and evaluating drug effects. Appropriate application of molecular imaging to drug discovery and development can markedly reduce costs and the time required for new drug development. This review focuses on the contributions of molecular imaging for drug discovery and development, particularly drug screening, pharmacokinetic, preclinical and clinical drug evaluation, and for personalized and lesionalized medicine.
Export Options
About this article
Cite this article as:
Ahn Byeong-Cheol, Applications of Molecular Imaging in Drug Discovery and Development Process, Current Pharmaceutical Biotechnology 2011; 12 (4) . https://dx.doi.org/10.2174/138920111795163904
DOI https://dx.doi.org/10.2174/138920111795163904 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
Call for Papers in Thematic Issues
Artificial Intelligence in Bioinformatics
Bioinformatics is an interdisciplinary field that analyzes and explores biological data. This field combines biology and information system. Artificial Intelligence (AI) has attracted great attention as it tries to replicate human intelligence. It has become common technology for analyzing and solving complex data and problems and encompasses sub-fields of machine ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Ellagic Acid Enhances the Efficacy of PI3K Inhibitor GDC-0941 in Breast Cancer Cells
Current Molecular Medicine Catabolic Fate and Pharmacokinetic Characterization of Trastuzumab Emtansine (T-DM1): an Emphasis on Preclinical and Clinical Catabolism
Current Drug Metabolism Cytokine Network: New Targeted Therapy for Pancreatic Cancer
Current Pharmaceutical Design Computational Studies in Drug Design Against Cancer
Anti-Cancer Agents in Medicinal Chemistry Cucurbitacin IIb from Ibervillea sonorae Induces Apoptosis and Cell Cycle Arrest via STAT3 Inhibition
Anti-Cancer Agents in Medicinal Chemistry Effects of Isolated Isoflavones Intake on Health
Current Medicinal Chemistry pH-Sensitive Polymeric Micelles for Programmable Drug and Gene Delivery
Current Pharmaceutical Design Emergence of Functionalized Nanomedicines in Cancer Chemotherapy: Recent Advancements, Current Challenges and Toxicity Considerations
Recent Patents on Nanomedicine Nitric Oxide-Derived Oxidants with a Focus on Peroxynitrite: Molecular Targets,Cellular Responses and Therapeutic Implications
Current Pharmaceutical Design Synthesis and Cytotoxicity of Two Active Metabolites of Larotaxel
Anti-Cancer Agents in Medicinal Chemistry Better Predictive Value of Cancer Antigen125 (CA125) as Biomarker in Ovary and Breast Tumors and its Correlation with the Histopathological Type/Grade of the Disease
Medicinal Chemistry Methotrexate Induced Pneumonitis: A Review Article
Current Respiratory Medicine Reviews Osteopontin is a Prognostic Factor in Patients with Advanced Gastric Cancer
Combinatorial Chemistry & High Throughput Screening Anti-Cancer Agent-Induced Nephrotoxicity
Anti-Cancer Agents in Medicinal Chemistry Patent Selections
Recent Patents on Biomedical Engineering (Discontinued) Peptides Targeting Angiogenesis Related Growth Factor Receptors
Current Pharmaceutical Design Foods and Drugs in the Management of Disease: A Case Study Comparing Omega-3 Fatty Acids and Aspirin for Inflammation
Current Pediatric Reviews Microbiome in Chronic Obstructive Pulmonary Disease: Role of Natural Products Against Microbial Pathogens
Current Medicinal Chemistry Targeting Cancer Stem Cells: Promises and Challenges
Anti-Cancer Agents in Medicinal Chemistry Biologic Agents in the Treatment of Psoriasis
Recent Patents on Inflammation & Allergy Drug Discovery