Xanthan Sulfuric Acid: An Efficient Bio-Supported and Recyclable Solid Acid Catalyst for the Synthesis of 2-minothiazole-5-carboxylates and 2-aminoselenazole-5-carboxylates

Author(s): Bowroju S. Kuarm, Janganati V. Madhav, Bhargavi Rajitha.

Journal Name: Letters in Organic Chemistry

Volume 8 , Issue 8 , 2011

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Abstract:

An efficient method has been developed for the synthesis of 2-amino thiazole and selenazole-5-carboxylates from β-ketoesters, thiourea or seleno urea and N-bromo succinamide by using Xanthan sulfuric acid as a solid acid catalyst. The reaction work-up is very simple and the catalyst can be easily separated from the reaction mixture and reused several times in subsequent reactions.

Keywords: Bio-supported, N-bromo succinamide(NBS), recyclable, selenazoles, thiazoles, Xanthan sulfuric acid, inflammation, hypertension, bacterial, HIV infections

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Article Details

VOLUME: 8
ISSUE: 8
Year: 2011
Page: [549 - 553]
Pages: 5
DOI: 10.2174/157017811797249443
Price: $65

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