Abstract
An efficient method for the three- or pseudo five-component synthesis of mono- and bis-2-amino-4H-pyrans in excellent yields using Alum (KAl(SO4)2.12H2O) as recyclable catalyst is described. The present methodology offers several advantages such as excellent yields, simple procedures, shorter reaction times, milder conditions and the catalysts exhibited remarkable reusable activity.
Keywords: Alum (KAl(SO4)2.12H2O), 2-Amino-4H-pyrans, 4-Hydroxycoumarin, 1,4-dihydropyridines, triethylamine, aldehydes, aminophosphonates, malononitrile, Spectrophotometer, nitrobenzaldehyde
Letters in Organic Chemistry
Title: Mono- and Bis-2-amino-4H-pyrans: Alum Catalyzed Three- or Pseudo Five-Component Reaction of 4-Hydroxycoumarin, Malononitrile and Aldehydes
Volume: 8 Issue: 2
Author(s): Ali Reza Karimi and Cyrus Eslami
Affiliation:
Keywords: Alum (KAl(SO4)2.12H2O), 2-Amino-4H-pyrans, 4-Hydroxycoumarin, 1,4-dihydropyridines, triethylamine, aldehydes, aminophosphonates, malononitrile, Spectrophotometer, nitrobenzaldehyde
Abstract: An efficient method for the three- or pseudo five-component synthesis of mono- and bis-2-amino-4H-pyrans in excellent yields using Alum (KAl(SO4)2.12H2O) as recyclable catalyst is described. The present methodology offers several advantages such as excellent yields, simple procedures, shorter reaction times, milder conditions and the catalysts exhibited remarkable reusable activity.
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Cite this article as:
Reza Karimi Ali and Eslami Cyrus, Mono- and Bis-2-amino-4H-pyrans: Alum Catalyzed Three- or Pseudo Five-Component Reaction of 4-Hydroxycoumarin, Malononitrile and Aldehydes, Letters in Organic Chemistry 2011; 8 (2) . https://dx.doi.org/10.2174/157017811794697421
DOI https://dx.doi.org/10.2174/157017811794697421 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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