Synthesis of Trisubstituted-4H-Pyrans via Unexpected Cycloaddition of Aldehydes with Acetylenic Ketones Mediated by DMAP and 2,4- Pentanedione

Title: Synthesis of Trisubstituted-4H-Pyrans via Unexpected Cycloaddition of Aldehydes with Acetylenic Ketones Mediated by DMAP and 2,4- Pentanedione

Volume: 6 Issue: 7

Author(s): Bin Hu, Qing-Fa Zhou, Kai Tang and Song Xue

Affiliation:

Keywords: Cycloaddition, acetylenic ketones, aldehydes, 4H-pyran, DMAP, 2,4-pentanedione

Abstract: A cycloaddition of aldehydes and acetylenic ketones mediated by 4-dimethylaminopyridine and 2,4- pentanedione is reported. The method supplies a facile way to synthesize 3,4,5-trisubstituted-4H-pyrans in moderate to good yields under mild conditions.

Cite this article as:

Hu Bin, Zhou Qing-Fa, Tang Kai and Xue Song, Synthesis of Trisubstituted-4H-Pyrans via Unexpected Cycloaddition of Aldehydes with Acetylenic Ketones Mediated by DMAP and 2,4- Pentanedione, Letters in Organic Chemistry 2009; 6 (7) . https://dx.doi.org/10.2174/157017809789869438