N-Substituted Amides as Chiral Ligands for Catalytic Asymmetric Reactions

Author(s): Ji Zhang, Hai-Bing Zhou, Ru-Gang Xie.

Journal Name: Current Organic Chemistry

Volume 6 , Issue 10 , 2002

Abstract:

In this review we introduced many kinds of bifunctional N-substituted amides, including phosphinamides and phosphoramides, squaramides, sulfonamides and so on which were applied to the asymmetric reactions. More emphasis were given to the asymmetric borane reduction of prochiral ketones, the reaction conditions and mechanisms were discussed systematically. At the same time, other reactions, including asymmetric addition, Diels-Alder reaction and Aldol reactions catalyzed by chiral N-substituted amides were also reviewed.

Keywords: N-Substituted Amides, Chiral Ligands, squaramides

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Article Details

VOLUME: 6
ISSUE: 10
Year: 2002
Page: [865 - 890]
Pages: 26
DOI: 10.2174/1385272023373806
Price: $58

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