Ytterbium triflate, Yb(OTf)3, is a versatile Lewis acid that has high catalytic activity in many organic reactions, including aldol,
Michael, Mannich, Friedel-Crafts, Diels-Alder, and some other types of reactions. Less than 10 mol% of Yb(OTf)3 is normally sufficient
for most organic transformations and can be recovered and re-used without loss of catalytic activity. In addition, Yb(OTf)3 is very stable
and its catalyzed reactions can be carried out in both organic solvents and aqueous conditions.
Keywords: Ytterbium triflate, Catalyst, Aldol condensation, Michael addition, Mannich reaction, Friedel-crafts, Diels-alder.
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