Ytterbium Triflate: A Versatile Catalyst in Organic Synthesis

Author(s): Lang-Jun Zhang , He-Lin Lu , Zong-Wen Wu , Yun-Sheng Huang .

Journal Name: Current Organic Chemistry

Volume 17 , Issue 23 , 2013

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Ytterbium triflate, Yb(OTf)3, is a versatile Lewis acid that has high catalytic activity in many organic reactions, including aldol, Michael, Mannich, Friedel-Crafts, Diels-Alder, and some other types of reactions. Less than 10 mol% of Yb(OTf)3 is normally sufficient for most organic transformations and can be recovered and re-used without loss of catalytic activity. In addition, Yb(OTf)3 is very stable and its catalyzed reactions can be carried out in both organic solvents and aqueous conditions.

Keywords: Ytterbium triflate, Catalyst, Aldol condensation, Michael addition, Mannich reaction, Friedel-crafts, Diels-alder.

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Article Details

Year: 2013
Page: [2906 - 2920]
Pages: 15
DOI: 10.2174/138527281723131218135830
Price: $58

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