Abstract
The present mini-review explores the current methods used for the delivery of antiseptics and topical antimicrobials. Relevance of hand scrub with antiseptic liquid soap (e.g. chlorhexidine, PVP-iodine, triclosan) and alcohol-based hand rub is discussed and compared in terms of bactericidal activity, skin tolerance, and medical staff observance. New strategies for antibacterial delivery focus on the challenge of colloidal drug carrier such as liposomes, micro- and nanoparticles enabling sustained bactericidal effect and effective bacterial targeting.
Keywords: Antisepsis, disinfection, biocides, alcohol-based rubs, hand scrubs, iposomes, microparticles, nanoparticles
Current Drug Delivery
Title: Current and New Strategies for the Delivery of Antiseptic Agents
Volume: 3 Issue: 3
Author(s): Helene Constant, Francoise Falson and Fabrice Pirot
Affiliation:
Keywords: Antisepsis, disinfection, biocides, alcohol-based rubs, hand scrubs, iposomes, microparticles, nanoparticles
Abstract: The present mini-review explores the current methods used for the delivery of antiseptics and topical antimicrobials. Relevance of hand scrub with antiseptic liquid soap (e.g. chlorhexidine, PVP-iodine, triclosan) and alcohol-based hand rub is discussed and compared in terms of bactericidal activity, skin tolerance, and medical staff observance. New strategies for antibacterial delivery focus on the challenge of colloidal drug carrier such as liposomes, micro- and nanoparticles enabling sustained bactericidal effect and effective bacterial targeting.
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Cite this article as:
Constant Helene, Falson Francoise and Pirot Fabrice, Current and New Strategies for the Delivery of Antiseptic Agents, Current Drug Delivery 2006; 3 (3) . https://dx.doi.org/10.2174/156720106777731055
DOI https://dx.doi.org/10.2174/156720106777731055 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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