Abstract
Non-invasive stimulation of the human brain to improve depressive symptoms is increasingly finding its way in clinical settings as a viable form of somatic treatment. Following successful modulation of neural excitability with subsequent antidepressant effects, neural polarization by administrating weak direct currents to the scalp has gained renewed interest. A new wave of basic and clinical studies seems to underscore the potential therapeutic value of direct current stimulation in the treatment of depression. Issues concerning the lack of mechanistic insights into the workings of modifying brain function through neural polarization and how this process translates to its antidepressant properties calls for additional research. The range of its clinical applicability has yet to be established.
Keywords: Depressive disorder, non-invasive brain stimulation, transcranial direct current stimulation, treatment.
CNS & Neurological Disorders - Drug Targets
Title:Current Directions in Non-Invasive Low Intensity Electric Brain Stimulation for Depressive Disorder
Volume: 13 Issue: 6
Author(s): Dennis J.L.G. Schutter and Alexander T. Sack
Affiliation:
Keywords: Depressive disorder, non-invasive brain stimulation, transcranial direct current stimulation, treatment.
Abstract: Non-invasive stimulation of the human brain to improve depressive symptoms is increasingly finding its way in clinical settings as a viable form of somatic treatment. Following successful modulation of neural excitability with subsequent antidepressant effects, neural polarization by administrating weak direct currents to the scalp has gained renewed interest. A new wave of basic and clinical studies seems to underscore the potential therapeutic value of direct current stimulation in the treatment of depression. Issues concerning the lack of mechanistic insights into the workings of modifying brain function through neural polarization and how this process translates to its antidepressant properties calls for additional research. The range of its clinical applicability has yet to be established.
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Schutter J.L.G. Dennis and Sack T. Alexander, Current Directions in Non-Invasive Low Intensity Electric Brain Stimulation for Depressive Disorder, CNS & Neurological Disorders - Drug Targets 2014; 13 (6) . https://dx.doi.org/10.2174/1871527313666140612115123
DOI https://dx.doi.org/10.2174/1871527313666140612115123 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
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