Abstract
An estimated 11% of the U.S. population has chronic kidney disease (CKD). Cardiovascular morbidity and mortality remain high among individuals with CKD and the higher mortality from cardiovascular disease persists even after adjusting for most of the traditional risk factors, suggesting the possible contributions of uremia-related, nontraditional risk factors. This has led to the current understanding that the pathophysiology of cardiovascular disease in CKD involves a complex interplay of both the traditional as well as nontraditional, uremia-related risk factors. Given the high cardiovascular morbidity and mortality, patients with CKD should be a target for aggressive cardiovascular risk reduction.
Keywords: Acute coronary syndrome, anemia, cardiovascular disease, chronic kidney disease, dialysis, dyslipidemia, glomerular filtration rate, hypertension, outcomes, uremia, secondary prevention
Cardiovascular & Hematological Agents in Medicinal Chemistry
Title:Interrelationship between Chronic Kidney Disease and Risk of Cardiovascular Diseases
Volume: 11 Issue: 1
Author(s): German T. Hernandez, Michael Sippel and Debabrata Mukherjee
Affiliation:
Keywords: Acute coronary syndrome, anemia, cardiovascular disease, chronic kidney disease, dialysis, dyslipidemia, glomerular filtration rate, hypertension, outcomes, uremia, secondary prevention
Abstract: An estimated 11% of the U.S. population has chronic kidney disease (CKD). Cardiovascular morbidity and mortality remain high among individuals with CKD and the higher mortality from cardiovascular disease persists even after adjusting for most of the traditional risk factors, suggesting the possible contributions of uremia-related, nontraditional risk factors. This has led to the current understanding that the pathophysiology of cardiovascular disease in CKD involves a complex interplay of both the traditional as well as nontraditional, uremia-related risk factors. Given the high cardiovascular morbidity and mortality, patients with CKD should be a target for aggressive cardiovascular risk reduction.
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Cite this article as:
T. Hernandez German, Sippel Michael and Mukherjee Debabrata, Interrelationship between Chronic Kidney Disease and Risk of Cardiovascular Diseases, Cardiovascular & Hematological Agents in Medicinal Chemistry 2013; 11 (1) . https://dx.doi.org/10.2174/1871525711311010007
DOI https://dx.doi.org/10.2174/1871525711311010007 |
Print ISSN 1871-5257 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6182 |
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Medicinal Plants with Beneficial Properties on Diabetes and Hypertension
Diabetes and hypertension are real scourges of the 21st century. It is imperative to act in order to find innovative solutions to this problem. Taking medications such as hypoglycemic and antihypertensive drugs may aggravate certain underlying comorbidities, such as chronic kidney disease and cardiovascular disease. This significant drawback therefore requires ...read more
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