Abstract
A predisposing weakness of the vessel wall has been assumed in patients with spontaneous cervical artery dissections (sCAD). Skin biopsies from many patients with sCAD show mild connective tissue alterations. However, their assessment depends on an invasive and highly specialized technique. Clinical signs of connective tissue disease are absent in the majority of CAD patients. In this review we document that only very few CAD patients are affected by known inherited connective tissue disorders like Ehlers-Danlos syndrome, Marfan syndrome or Osteogenesis Imperfecta. In a second part of this review we discuss the possible role of unrecognized or unknown forms of connective tissue disorders in the etiology of CAD.
Keywords: Connective Tissue, spontaneous cervical artery dissections (sCAD), Osteogenesis, Ehlers-Danlos syndrome, etiology
Current Molecular Medicine
Title: The Association of Connective Tissue Disorders with Cervical Artery Dissections
Volume: 9 Issue: 2
Author(s): Caspar Grond-Ginsbach and Stephanie Debette
Affiliation:
Keywords: Connective Tissue, spontaneous cervical artery dissections (sCAD), Osteogenesis, Ehlers-Danlos syndrome, etiology
Abstract: A predisposing weakness of the vessel wall has been assumed in patients with spontaneous cervical artery dissections (sCAD). Skin biopsies from many patients with sCAD show mild connective tissue alterations. However, their assessment depends on an invasive and highly specialized technique. Clinical signs of connective tissue disease are absent in the majority of CAD patients. In this review we document that only very few CAD patients are affected by known inherited connective tissue disorders like Ehlers-Danlos syndrome, Marfan syndrome or Osteogenesis Imperfecta. In a second part of this review we discuss the possible role of unrecognized or unknown forms of connective tissue disorders in the etiology of CAD.
Export Options
About this article
Cite this article as:
Grond-Ginsbach Caspar and Debette Stephanie, The Association of Connective Tissue Disorders with Cervical Artery Dissections, Current Molecular Medicine 2009; 9 (2) . https://dx.doi.org/10.2174/156652409787581547
DOI https://dx.doi.org/10.2174/156652409787581547 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Climate Change, Climate Variability and Brucellosis
Recent Patents on Anti-Infective Drug Discovery Management and Outcomes of Aortic Dissection in Pregnancy with Marfan Syndrome: A Systematic Review
Current Vascular Pharmacology Craniocervical Dissections: Radiologic Findings, Pitfalls, Mimicking Diseases: A Pictorial Review
Current Medical Imaging Role, Function and Therapeutic Potential of microRNAs in Vascular Aging
Current Vascular Pharmacology RNA-Mediated Therapeutics: From Gene Inactivation to Clinical Application
Current Topics in Medicinal Chemistry Screening Aortic Drug Treatments Through Arterial Compliance Measurements
Current Vascular Pharmacology Arrhythmias and Left Ventricular Hypertrabeculation/Noncompaction
Current Pharmaceutical Design The Shock of the New: Progress in Schizophrenia Genomics
Current Genomics Molecular Diagnosis and Treatment of Multiple Endocrine Neoplasia Type 2B in Ethnic Han Chinese
Endocrine, Metabolic & Immune Disorders - Drug Targets Pleiotropic Effects of ARB in Vascular Metabolism - Focusing on Atherosclerosis-Based Cardiovascular Disease
Current Vascular Pharmacology Complications of the Chest Wall and the Respiratory System After Surgery and Functional Performance
Current Respiratory Medicine Reviews Drug Repositioning: A Unique Approach to Refurbish Drug Discovery
Current Drug Discovery Technologies Actions of Selected Cardiovascular Hormones on Arterial Stiffness and Wave Reflections
Current Pharmaceutical Design Targeting Fibrosis in Systemic Sclerosis
Endocrine, Metabolic & Immune Disorders - Drug Targets Developments in Non-Surgical Therapies for Abdominal Aortic Aneurysm
Current Vascular Pharmacology Common Genetic Conditions of Ischemic Stroke to Keep in Mind
Current Molecular Medicine Sudden Unexpected Death in Infancy (SUDI) — The Role of the Pathologist
Current Pediatric Reviews Management of Incidental Findings in the Era of Next-generation Sequencing
Current Genomics Novel Biomarkers Assessing the Calcium Deposition in Coronary Artery Disease
Current Medicinal Chemistry Molecular Basis of Young Ischemic Stroke
Current Medicinal Chemistry