Crocin, the most important active constituent of saffron, has been proposed to be effective
in the management of various diseases including renal failures. It also prevented nephrotoxicity induced
by carbon tetrachloride, gentamicin, streptozotocin, glucose, patulin, and zearalenone in experimental
models. However, more investigations should be done to confirm the antidotal effects of
crocin in human being. The present study was designed to review the scientific literature about the
protective effects of crocin against nephrotoxic agents.
Keywords: Antioxidant, crocin, kidney, nephrotoxic, toxic agents, renal failures.
Rights & PermissionsPrintExport