Introduction: One challenging problem in patients suffering from Diabetes Mellitus (DM)
is the elevate incidence of cardiovascular events. Exercise has been proved useful in reducing cardiovascular
risks in these patients. However, both type 1 and 2 DM significantly affect the cardiovascular
response during exercise. Therefore, on one side exercise is considered to be a valid therapeutic
tool for DM, whereas on the other side during exercise these patients may experience troubles in the
Background: Several impairments at central and at peripheral level have been reported during exercise
in both types of DM. For example, sympathetic dysfunctions have been demonstrated in type 1
and 2 DM. Furthermore, impairments in hemodynamics have been often reported. The purpose of the
present paper is to briefly review the latest data on the role played by type 1 and 2 DM in the cardiovascular
regulation during dynamic exercise.
Conclusion: Hemodynamic dysfunctions may develop in both type 1 and 2 DM during exercise.
However, these cardiovascular dys-regulations are different between the two kinds of diabetes.