Search Result "submicromolar"


Inhibition of Hepatobiliary Transporters by A Novel Kinase Inhibitor Contributes to Hepatotoxicity in Beagle Dogs

Journal: Drug Metabolism Letters
Volume: 7 Issue: 1 Year: 2013 Page: 15-22
Author(s): John Scott Daniels,Yurong Lai,Sarah South,Po-Chang Chiang,Daniel Walker,Bo Feng,Rouchelle Mireles,Laurence O. Whiteley,Jeremy W. Mckenzie,Jeffrey Stevens,Robert Mourey,David Anderson,John W. Davis II

Neglected Aspects of Drug Discovery - Microbiological Aspects

Journal: Current Clinical Pharmacology
Volume: 8 Issue: 1 Year: 2013 Page: 73-80
Author(s): Jacob Golenser, Nicholas Hunt

Survey of Recent Literature Related to the Biologically Active 4(3H)-Quinazolinones Containing Fused Heterocycles

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 6 Year: 2013 Page: 794-814
Author(s): Martine Demeunynck,Isabelle Baussanne

Recent Advances Toward Improving the Bioavailability of Neuronal Nitric Oxide Synthase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 803-812
Author(s): He Huang, Richard B. Silverman

Synthesis and HIV-1 Inhibitory Activities of Dicaffeoyl and Digalloyl Esters of Quinic Acid Derivatives

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 5 Year: 2013 Page: 724-733
Author(s): C. O.R. Junior, S. C. Verde, C. A.M. Rezende, W. Caneschi, M. R.C. Couri, B. R. McDougall, W. E. Robinson, Jr., M. V. de Almeida

Hemisynthesis of Selected Embelin Analogs and Investigation of their Proapoptotic Activity Against Cancer Cells

Journal: Medicinal Chemistry
Volume: 9 Issue: 8 Year: 2013 Page: 1028-1034
Author(s): Guillaume Viault,Katragadda Suresh Babu,Fabien Gautier,Sophie Barillé-Nion,Philippe Juin,Olivier Tasseau,René Grée

Developing FGFR4 Inhibitors As Potential Anti-Cancer Agents Via In Silico Design, Supported by In Vitro and Cell-Based Testing

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1203-1217
Author(s): H. K. Ho, G. Nemeth, Y. R. Ng, E. Pang, C. Szantai-Kis, L. Zsakai, N. Breza, Z. Greff, Z. Horvath, J. Pato, I. Szabadkai, B. Szokol, F. Baska, L. Orfi, A. Ullrich, G. Keri, B. T. Chua

Review Article

Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 31 Year: 2013 Page: 3855-3871
Author(s): Tomo Yonezawa,Riho Kurata,Kaori Yoshida,Masanori A. Murayama,Xiaofeng Cui,Akihiko Hasegawa

The Identification of the SIRT1 Activator SRT2104 as a Clinical Candidate

Journal: Letters in Drug Design & Discovery
Volume: 10 Issue: 9 Year: 2013 Page: 793-797
Author(s): Pui Yee Ng, Jean E. Bemis, Jeremy S. Disch, Chi B. Vu, Christopher J. Oalmann, Amy V. Lynch, David P. Carney, Thomas V. Riera, Jeffrey Song, Jesse J. Smith, Siva Lavu, Angela Tornblom, Meghan Duncan, Marie Yeager, Kristina Kriksciukaite, Akanksha Gupta, Vipin Suri, Peter J. Elliot, Jill C. Milne, Joseph J. Nunes, Michael R. Jirousek, George P. Vlasuk, James L. Ellis, Robert B. Perni

Phenolic Compounds as Antioxidants: Carbonic Anhydrase Isoenzymes Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13 Issue: 3 Year: 2013 Page: 408-430
Author(s): Ilhami Gulcin,Sukru Beydemir

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