Search Result "structure-based design"


Impact of Computational Structure-based Methods on Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 20 Year: 2014 Page: 3380-3386
Author(s): Charles H. Reynolds

Structure-Based Drug Design to Overcome Drug Resistance: Challenges and Opportunities

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 5 Year: 2014 Page: 687-693
Author(s): Rafaela S. Ferreira,Adriano D. Andricopulo

Structure-Based Drug Design of Novel MARK-3 Inhibitors in Cancer

Journal: Current Bioactive Compounds
Volume: 10 Issue: 2 Year: 2014 Page: 131-138
Author(s): Josiana G. de Araujo Volpini,Ricardo P. Rodrigues,Leonardo B. Federico,Carlos H.T. de Paula da Silva

New Ligands of the Tubulin Colchicine Site Based on X-Ray Structures

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 20 Year: 2014 Page: 2231-2252
Author(s): Raquel Alvarez,Manuel Medarde,Rafael Pelaez

Structure-Based β-Secretase (BACE1) Inhibitors

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 20 Year: 2014 Page: 3373-3379
Author(s): Timea Polgar,Gyorgy M. Keseru

Structure-Based Virtual Screening for Drug Discovery: Principles, Applications and Recent Advances

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 16 Year: 2014 Page: 1923-1938
Author(s): Evanthia Lionta,George Spyrou,Demetrios K. Vassilatis,Zoe Cournia

Free Energy Calculations to Estimate Ligand-Binding Affinities in Structure-Based Drug Design

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 20 Year: 2014 Page: 3323-3337
Author(s): M. Rami Reddy,C. Ravikumar Reddy,R. S. Rathore,Mark D. Erion,P. Aparoy,R. Nageswara Reddy,P. Reddanna

Identifying Structural Features Related to the Biological Activity of a Series of AT1 Antagonists from Fragment-based Drug Design

Journal: Protein & Peptide Letters
Volume: 21 Issue: 6 Year: 2014 Page: 542-549
Author(s): Danielle da C. Silva,Vinícius G. Maltarollo,Kathia M. Honorio

Prediction of Cytochrome P450 Mediated Metabolism of Designer Drugs

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1365-1373
Author(s): Line Marie Nielsen,Kristian Linnet,Lars Olsen,Patrik Rydberg

SMOTER, A Structured Motif Finder Based on an Exhaustive Tree-Based Algorithm

Journal: Current Bioinformatics
Volume: 9 Issue: 1 Year: 2014 Page: 34-43
Author(s): Siavash Sheikhizadeh,Samin Hosseini

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