Search Result "small molecular weight inhibitors"


A Leap into the Chemical Space of Protein-Protein Interaction Inhibitors

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 30 Year: 2012 Page: 4648-4667
Author(s): B. O. Villoutreix,C. M. Labbe,D. Lagorce,G. Laconde,O. Sperandio

Predicting the Metabolic Pathways of Small Molecules Based on Their Physicochemical Properties

Journal: Protein & Peptide Letters
Volume: 19 Issue: 12 Year: 2012 Page: 1250-1256
Author(s): Chun-Rong Peng,Wen-Cong Lu,Bing Niu,Min-Jie Li,Xiao-YanYang,Mi-Lin Wu

The Applicability of Molecular Descriptors for Designing an Electrospray Ionization Mass Spectrometry Compatible Library for Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 1 Year: 2012 Page: 806-815
Author(s): Jennifer C. Copeland, Levi J. Zehr, Ronald L. Cerny, Robert Powers

New Parenteral Anticoagulants: Focus on Factor Xa and Thrombin Inhibitors

Journal: Current Drug Discovery Technologies
Volume: 9 Issue: 2 Year: 2012 Page: 129-136
Author(s): Ingo Ahrens,Christoph Bode

Ligand- and Protein-Based Modeling Studies of the Inhibitors of Human Cytochrome P450 2D6 and a Virtual Screening for Potential Inhibitors from the Chinese Herbal Medicine, Scutellaria baicalensis (Huangqin,Baikal Skullcap)

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 1 Year: 2012 Page: 36-80
Author(s): Sui-Lin Mo, Wei-Feng Liu, Yuling Chen, Hai-Bin Luo, Lai-Bao Sun, Xiao-Wu Chen, Zhi-Wei Zhou, Kevin B. Sneed, Chun Guang Li, Yao-Min Du, Jun Liang, Shu-Feng Zhou

P53 Mdm2 Inhibitors

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 30 Year: 2012 Page: 4668-4678
Author(s): Kareem Khoury,Alex Domling

Malleability and Versatility of Cytochrome P450 Active Sites Studied by Molecular Simulations

Journal: Current Drug Metabolism
Volume: 13 Issue: 2 Year: 2012 Page: 190-196
Author(s): Chris Oostenbrink, Anita de Ruiter, Jozef Hritz, Nico Vermeulen

Molecular Dynamics Simulations of CYP2E1

Journal: Medicinal Chemistry
Volume: 8 Issue: 2 Year: 2012 Page: 208-221
Author(s): Jue Li, Dong-Qing Wei, Jing-Fang Wang, Zheng-Tian Yu, Kuo-Chen Chou

Targeting Mitogen-Activated Protein Kinase Phosphatase-1 (MKP-1): Structure-Based Design of MKP-1 Inhibitors and Upregulators

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 163-173
Author(s): M. R. Doddareddy, T. Rawling, A. J. Ammit

Insights into Angiogenesis in Non-Small Cell Lung Cancer: Molecular Mechanisms, Polymorphic Genes, and Targeted Therapies

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 7 Issue: 1 Year: 2012 Page: 118-131
Author(s): Ramon Andrade de Mello, Bruno M. Costa, Rui M. Reis, Venceslau Hespanhol

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