Search Result "prediction of lead compounds."


Novel, Acidic CCR2 Receptor Antagonists: Lead Optimization

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 4 Year: 2007 Page: 263-271
Author(s): O. A. Dasse, J. L. Evans, H.-X. Zhai, D. Zou, J. T. Kintigh, F. Chan, K. Hamilton, E. Hill, J. B. Eckman, P. J. Higgins, A. Volosov, P. Collart, J.-M. Nicolas, R.K. Kondru, C.E. Schwartz

Computer-Assisted Methods in Chemical Toxicity Prediction

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 5 Year: 2007 Page: 499-507
Author(s): C. Gopi Mohan, Tamanna Gandhi, Divita Garg, Ranajit Shinde

From Drug Target to Leads-Sketching A Physicochemical Pathway for Lead Molecule Design In Silico

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 3 Year: 2007 Page: 3454-3470
Author(s): S. A. Shaikh, T. Jain, G. Sandhu, N. Latha, B. Jayaram

Targeting Carcinogen Metabolism by Dietary Cancer Preventive Compounds

Journal: Current Cancer Drug Targets
Volume: 7 Issue: 5 Year: 2007 Page: 416-424
Author(s): Siwang Yu, Ah-Ng Kong

In Silico Prediction of Human Plasma Protein Binding Using Hologram QSAR

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 7 Year: 2007 Page: 502-509
Author(s): Tiago L. Moda, Carlos A. Montanari, Adriano D. Andricopulo

Evaluation of Human Pharmacokinetics, Therapeutic Dose and Exposure Predictions Using Marketed Oral Drugs

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 463-479
Author(s): D.F. McGinnity, J. Collington, R.P. Austin, R.J. Riley

Computer Prediction of Cardiovascular and Hematological Agents by Statistical Learning Methods

Journal: Cardiovascular & Hematological Agents in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2007 Page: 11-19
Author(s): X. Chen, H. Li, C. W. Yap, C. Y. Ung, L. Jiang, Z. W. Cao, Y. X. Li, Y. Z. Chen

CYP-Mediated Clozapine Interactions: How Predictable Are They?

Journal: Current Drug Metabolism
Volume: 8 Issue: 4 Year: 2007 Page: 307-313
Author(s): Manoranjenni Chetty, Michael Murray

Predictive QSAR Modeling Workflow, Model Applicability Domains, and Virtual Screening

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 3 Year: 2007 Page: 3494-3504
Author(s): Alexander Tropsha, Alexander Golbraikh

An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1600-1629
Author(s): Jeffrey S. Albert, Niklas Blomberg, Alexander L. Breeze, Alastair J. H. Brown, Jeremy N. Burrows, Philip D. Edwards, Rutger H. A. Folmer, Stefan Geschwindner, Ed J. Griffen, Peter W. Kenny, Thorsten Nowak, Lise-Lotte Olsson, Hitesh Sanganee, Adam B. Shapiro

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