Search Result "pi3k."


Research Article

Design and Synthesis of Coumarin Derivatives as Novel PI3K Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 395-403
Author(s): Chen-Chen Ma,Zhao-Peng Liu

Research Article

Discovery of 6-benzamide Containing 4-phenylquinazoline Derivatives as Novel PI3K? Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 2 Year: 2017 Page: 167-174
Author(s): Minhang Xin, Yuan-Yuan Hei, Hao Zhang, Xiao-Xiao Xie, Shuai Mao, Sai-Jie Zuo, San-Qi Zhang

Review Article

PI3K/Akt/mTOR Intracellular Pathway and Breast Cancer: Factors, Mechanism and Regulation

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 1 Year: 2017 Page: 1633-1638
Author(s): Var Ruchi Sharma,Girish Kumar Gupta,A. K. Sharma,Navneet Batra,Daljit K. Sharma,Amit Joshi,Anil K. Sharma

Review Article

PI3K/Akt Pathway: A Potential Therapeutic Target for Chronic Pain

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 1 Year: 2017 Page: 1860-1868
Author(s): Shu-Ping Chen,Ya-Qun Zhou,Dai-Qiang Liu,Wen Zhang,Anne Manyande,Xue-Hai Guan,Yu-ke Tian,Da-Wei Ye,Deeq Mohamed Omar

Research Article

3D-QSAR, Virtual Screening, Docking and Design of Dual PI3K/mTOR Inhibitors with Enhanced Antiproliferative Activity

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 20 Issue: 4 Year: 2017 Page: 292-303
Author(s): Jelena Oluić,Katarina Nikolic,Jelica Vucicevic,Zarko Gagic,Slavica Filipic,Danica Agbaba

Review Article

Targeting the Akt/PI3K Signaling Pathway as a Potential Therapeutic Strategy for the Treatment of Pancreatic Cancer

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 1 Year: 2017 Page: 1321-1331
Author(s): Safieh Ebrahimi,Mina Hosseini,Soodabeh Shahidsales,Mina Maftouh,Gordon A. Ferns,Majid Ghayour-Mobarhan,Seyed Mahdi Hassanian,Amir Avan

Research Article

Molecular Docking Studies of Novel Thiosemicarbazone-based Indoles as Potential PI3Kα Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 11 Year: 2017 Page: 1252-1258
Author(s): Dima A. Sabbah,Kamal Sweidan

Research Article

Polyphyllin II Restores Sensitization of the Resistance of PC-9/ZD Cells to Gefitinib by a Negative Regulation of the PI3K/Akt/mTOR Signaling Pathway

Journal: Current Cancer Drug Targets
Volume: 17 Issue: 4 Year: 2017 Page: 376-385
Author(s): Ruzhen Zheng,Hao Jiang,Jinhui Li,Xinge Liu,Hongwei Xu

Review Article

The PI3K/AKT/mTOR-Signal Transduction Pathway as Drug Target in Triple-Negative Breast Cancer

Journal: Clinical Cancer Drugs
Volume: 4 Issue: 1 Year: 2017 Page: 47-58
Author(s): Jens C. Hahne,Jorg B. Engel,Arnd Honig,Susanne R. Meyer,Domenico Zito,Andrea Lampis,Nicola Valeri

Review Article

Phosphoinositide-3-kinases as the Novel Therapeutic Targets for the Inflammatory Diseases: Current and Future Perspectives

Journal: Current Drug Targets
Volume: 18 Issue: 14 Year: 2017 Page: 1622-1640
Author(s): Preeti Vyas,Divya Vohora

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