Search Result "p70S6K"


Pharmacologic Inhibition of mTOR Improves Lapatinib Sensitivity in HER2-Overexpressing Breast Cancer Cells with Primary Trastuzumab Resistance

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2012 Page: 151-162
Author(s): Sylvia S. Gayle, Samuel L.M. Arnold, Ruth M. ORegan, Rita Nahta

Wnt1 Inducible Signaling Pathway Protein 1 (WISP1) Targets PRAS40 to Govern β-Amyloid Apoptotic Injury of Microglia

Journal: Current Neurovascular Research
Volume: 9 Issue: 4 Year: 2012 Page: 239-249
Author(s): Yan Chen Shang,Zhao Zhong Chong,Shaohui Wang,Kenneth Maiese

The Quinoline Imidoselenocarbamate EI201 Blocks the AKT/mTOR Pathway and Targets Cancer Stem Cells Leading to a Strong Antitumor Activity

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2012 Page: 3031-3043
Author(s): E. Ibanez, A. Agliano, C. Prior, P. Nguewa, M. Redrado, I. Gonzalez-Zubeldia, D. Plano, J. A. Palop, C. Sanmartin, A. Calvo

Is the Autophagy Induced by Thiopurines Beneficial or Deleterious?

Journal: Current Drug Metabolism
Volume: 13 Issue: 9 Year: 2012 Page: 1267-1276
Author(s): Luis G. Guijarro,Irene D. Roman,Mª Dolores Fernandez-Moreno,Javier P. Gisbert,Borja Hernandez- Breijo

Targeting the Cancer Initiating Cell: The Ultimate Target for Cancer Therapy

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 13 Year: 2012 Page: 1784-1795
Author(s): James A. McCubrey, Linda S. Steelman, Stephen L. Abrams, Negin Misaghian, William H. Chappell,Jorg Basecke, Ferdinando Nicoletti, Massimo Libra, Giovanni Ligresti, Francac Stivala, Danijela Maksimovic-Ivanic,Sanja Mijatovic, Giuseppeo Montalto, Melchiorre Cervello, Piotr Laidler, Antonio Bonati, Camilla Evangelisti, Lucio Cocco,Alberto M. Martelli

Proteomic Classification of Breast Cancer

Journal: Current Drug Targets
Volume: 13 Issue: 12 Year: 2012 Page: 1495-1509
Author(s): Dalia Kamel,Bernadette Brady,Adel Tabchy,Gordon B. Mills,Bryan Hennessy

Neurosteroid PREGS Protects Neurite Growth and Survival of Newborn Neurons in the Hippocampal Dentate Gyrus of APPswe/PS1dE9 Mice

Journal: Current Alzheimer Research
Volume: 9 Issue: 3 Year: 2012 Page: 361-372
Author(s): Bingzhong Xu,Rong Yang,Fei Chang,Lei Chen,Guiqing Xie,Masahiro Sokabe,Ling Chen

Insulin-Like Growth Factor-I Molecular Pathways in Osteoblasts: Potential Targets for Pharmacological Manipulation

Journal: Current Molecular Pharmacology
Volume: 5 Issue: 2 Year: 2012 Page: 143-152
Author(s): Kristen E. Govoni

DYRK1A Kinase Inhibitors with Emphasis on Cancer

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 12 Issue: 1 Year: 2012 Page: 1315-1329
Author(s): A. Ionescu, F. Dufrasne, M. Gelbcke, I. Jabin, R. Kiss, D. Lamoral-Theys

GRK2 at the Control Shaft of Cellular Metabolism

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 2 Year: 2012 Page: 121-127
Author(s): Michele Ciccarelli, Ersilia Cipolletta, Guido Iaccarino

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