Search Result "myeloproliferative diseases"

Research Article

A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 19 Issue: 10 Year: 2016 Page: 824-833
Author(s): Anna Ngo,Ann Zhufang Koay,Christian Pecquet,Carmen C. Diaconu,Yasmine Ould-Amer,Qiwei Huang,Congbao Kang,Anders Poulsen,May Ann Lee,David Jenkins,Andrew Shiau,Stefan N. Constantinescu,Meng Ling Choong

Insights into the Structural Features Essential for JAK2 Inhibition and Selectivity

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 13 Year: 2016 Page: 1331-1355
Author(s): Chao Zhao,Daulat Bikram Khadka,Won-Jea Cho

New Insights into the Molecular Resistance Mechanisms of Chronic Myeloid Leukemia

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 4 Year: 2016 Page: 323-345
Author(s): Rui Huang,Qian Kang,Huimin Liu,Yuhua Li

Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 25 Year: 2016 Page: 2753-2764
Author(s): Liza Shrestha,Alexander Bolaender,Hardik J. Patel,Tony Taldone

Review Article

Circulating Advanced Oxidation Protein Products as Oxidative Stress Biomarkers and Progression Mediators in Pathological Conditions Related to Inflammation and Immune Dysregulation

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 34 Year: 2016 Page: 3862-3882
Author(s): Mariateresa Cristani,Antonio Speciale,Antonella Saija,Sebastiano Gangemi,Paola Lucia Minciullo,Francesco Cimino

Research Article

Protein Geranylgeranyltransferase Type 1 as a Target in Cancer

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 7 Year: 2016 Page: 563-571
Author(s): Nisar Ullah, Muhammad Mansha, Patrick J. Casey

Impact of Splicing Factor Mutations on Pre-mRNA Splicing in the Myelodysplastic Syndromes

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 1 Year: 2016 Page: 2333-2344
Author(s): Bon Ham Yip, Hamid Dolatshad, Swagata Roy, Andrea Pellagatti, Jacqueline Boultwood

Review Article

Quinoxaline Nucleus: A Promising Scaffold in Anti-cancer Drug Discovery

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 10 Year: 2016 Page: 1339-1352
Author(s): Alessandra C. Pinheiro,Thais C. Mendonça Nogueira,Marcus V.N. de Souza

Endothelial Cell Senescence and Inflammaging: MicroRNAs as Biomarkers and Innovative Therapeutic Tools

Journal: Current Drug Targets
Volume: 17 Issue: 4 Year: 2016 Page: 388-397
Author(s): Francesco Prattichizzo,Massimiliano Bonafè,Artan Ceka,Angelica Giuliani,Maria Rita Rippo,Massimo Re,Roberto Antonicelli,Antonio Domenico Procopio,Fabiola Olivieri

The Past, Present and Future Subclassification of Patients with Acute Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 17 Issue: 1 Year: 2016 Page: 6-19
Author(s): Rakel B. Forthun,Carina Hinrichs,Tara H. Dowling,Øystein Bruserud,Frode Selheim

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