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Mutations of Chromatin Structure Regulating Genes in Human Malignancies

Journal: Current Protein & Peptide Science
Volume: 17 Issue: 5 Year: 2016 Page: 411-437
Author(s): Jian Chen,Franklin H. Herlong,John R. Stroehlein,Lopa Mishra

Impact of Splicing Factor Mutations on Pre-mRNA Splicing in the Myelodysplastic Syndromes

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 1 Year: 2016 Page: 2333-2344
Author(s): Bon Ham Yip, Hamid Dolatshad, Swagata Roy, Andrea Pellagatti, Jacqueline Boultwood

Chemoresistance of Cancer Cells: Oncogenic Mutation of the p53 Tumor Suppressor Gene

Journal: Current Signal Transduction Therapy
Volume: 11 Issue: 1 Year: 2016 Page: 3-8
Author(s): Daisuke Uchida,Hitoshi Kawamata,Fujiyuki Inaba,Ichio Fukasawa,Takahiro Fujimori

Targeting the Ataxia Telangiectasia Mutated Protein in Cancer Therapy

Journal: Current Drug Targets
Volume: 17 Issue: 2 Year: 2016 Page: 139-153
Author(s): Donatella Vecchio,Guido Frosina

A Computational Study of Three Frequent Mutations of EGFR and their Effects on Protein Dimer Formation and Non-Small Cell Lung Cancer Drug Resistance

Journal: Current Bioinformatics
Volume: 11 Issue: 3 Year: 2016 Page: 382-391
Author(s): Zhiyong Shen,Debby D. Wang,Lichun Ma,Hong Yan,Maria P. Wong,Victor H.F. Lee

Biophysical Characterization of the Nucleoside Diphosphate Kinase of Leishmania major and Effect of the P95S Mutation

Journal: Protein & Peptide Letters
Volume: 23 Issue: 2 Year: 2016 Page: 99-106

Review Article

Identification of Small Molecule as a High Affinity β2 Agonist Promiscuously Targeting Wild and Mutated (Thr164Ile) β 2 Adrenergic Receptor in the Treatment of Bronchial Asthma

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 34 Year: 2016 Page: 5221-5233
Author(s): Srinivas Bandaru,Mallika Alvala,Jyothy Akka,Someshwar Rao Sagurthi,Anuraj Nayarisseri,Sanjeev Kumar Singh,Hema Prasad Mundluru

Research Article

Transforming Mutations of Jak3 (A573V and M511I) Show Differential Sensitivity to Selective Jak3 Inhibitors

Journal: Clinical Cancer Drugs
Volume: 3 Issue: 2 Year: 2016 Page: 131-137
Author(s): G. Steven Martinez, Jeremy A. Ross, Robert A. Kirken

Review Article

De Novo Design of New Inhibitor of Mutated Tyrosine-Kinase for the Myeloid Leukemia Treatment

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 33 Year: 2016 Page: 5057-5064
Author(s): Washington Pereira,Ihosvany Camps

Review Article

Triggering PIK3CA Mutations in PI3K/Akt/mTOR Axis: Exploration of Newer Inhibitors and Rational Preventive Strategies

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 39 Year: 2016 Page: 6039-6054
Author(s): Vivek Asati,Sanjay K. Bharti,Debarshi Kar Mahapatra,Vikas Asati,Ashok K. Budhwani

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