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Potential Strategies for Minimizing Mechanism-Based Inhibition of Cytochrome P450 3A4

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 1 Year: 2008 Page: 990-1000
Author(s): Shu-Feng Zhou

Mammalian Cytosine DNA Methyltransferase Dnmt1: Enzymatic Mechanism, Novel Mechanism-Based Inhibitors, and RNA-directed DNA Methylation

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 92-106
Author(s): Zeljko M. Svedruzic

Gene Therapy: The First Approved Gene-Based Medicines, Molecular Mechanisms and Clinical Indications

Journal: Current Molecular Pharmacology
Volume: 1 Issue: 1 Year: 2008 Page: 13-23
Author(s): J. K. Raty, J. T. Pikkarainen, T. Wirth, S. Yla-Herttuala

In Vitro Cytochrome P450 Inhibition and Induction

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 928-939
Author(s): Robert L. Walsky, Sherri E. Boldt

Inactivation of Indispensable Bacterial Proteins by Early Proteins of Bacteriophages:Implication in Antibacterial Drug Discovery

Journal: Current Protein & Peptide Science
Volume: 9 Issue: 3 Year: 2008 Page: 284-290
Author(s): S. Sau, P. Chattoraj, T. Ganguly, P. K. Chanda, N. C. Mandal

High-Content Screening and Mechanism-Based Evaluation of Estrogenic Botanical Extracts

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 4 Year: 2008 Page: 283-293
Author(s): Cassia R. Overk, Ping Yao, Shaonong Chen, Shixing Deng, Ayano Imai, Matthew Main, Andreas Schinkovitz, Norman R. Farnsworth, Guido F. Pauli, Judy L. Bolton

Transient Disruption of Fear-Related Memory by Post-Retrieval Inactivation of Gastrin-Releasing Peptide or N-Methyl-D-Aspartate Receptors in the Hippocampus

Journal: Current Neurovascular Research
Volume: 5 Issue: 1 Year: 2008 Page: 21-27
Author(s): Rafael Roesler, Tatiana Luft, Olavo B. Amaral, Gilberto Schwartsmann

An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes

Journal: Drug Metabolism Letters
Volume: 2 Issue: 1 Year: 2008 Page: 51-59
Author(s): Loren M. Berry, Zhiyang Zhao

In Vitro Metabolism Studies of New Adenosine A Receptor Antagonists

Journal: Drug Metabolism Letters
Volume: 2 Issue: 4 Year: 2008 Page: 301-307
Author(s): Gabriella Marucci, Sara Finaurini, Michela Buccioni, Carmen Lammi, Meenakshisundaram Kandhavelu, Rosaria Volpini, Massimo Ricciutelli, Piero Angeli, Jan N.M. Commandeur, Gloria Cristalli

Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions

Journal: Current Drug Metabolism
Volume: 9 Issue: 5 Year: 2008 Page: 384-393
Author(s): Jiansong Yang, Mingxiang Liao, Magang Shou, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker, Amin Rostami-Hodjegan

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