Search Result "mechanism-based inactivation."


Drug-Drug Interactions via Mechanism-Based Cytochrome P450 Inactivation: Points to Consider for Risk Assessment from In Vitro Data and Clinical Pharmacologic Evaluation

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 449-462
Author(s): Karthik Venkatakrishnan, R. Scott Obach

Gene Inactivation in Caenorhabditis elegans

Journal: Current Genomics
Volume: 3 Issue: 2 Year: 2002 Page: 59-67
Author(s): Gert Jansen

Potential Strategies for Minimizing Mechanism-Based Inhibition of Cytochrome P450 3A4

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 1 Year: 2008 Page: 990-1000
Author(s): Shu-Feng Zhou

The Structure of Ribosome Inactivating Proteins

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 4 Issue: 5 Year: 2004 Page: 477-486
Author(s): Jon D. Robertus, Arthur F. Monzingo

Recent Progress in Research on Ribosome Inactivating Proteins

Journal: Current Protein & Peptide Science
Volume: 11 Issue: 1 Year: 2010 Page: 37-53
Author(s): T. B. Ng, Jack Ho Wong, Hexiang Wang

Impact of Time-Dependent Inactivation on the Estimation of Enzyme Kinetic Parameters for Midazolam

Journal: Drug Metabolism Letters
Volume: 3 Issue: 1 Year: 2009 Page: 45-53
Author(s): Craig Giragossian, Jennifer LaPerle, Rachel E. Kosa, Sarah Gillian

High Throughput Quantitative Assessment of CYP Inactivation Using 2 Concentration Points

Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 78-82
Author(s): Daniel Albaugh, Thomas Farrell, Michael Langan, W. George Lai

Cytotoxicity and Toxicity to Animals and Humans of Ribosome-Inactivating Proteins

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 4 Issue: 5 Year: 2004 Page: 513-521
Author(s): Maria Giulia Battelli

Thermal Inactivation and Conformational Lock of Bovine Carbonic Anhydrase

Journal: Protein & Peptide Letters
Volume: 19 Issue: 8 Year: 2012 Page: 852-858
Author(s): L. Alaei,A. A.Moosavi-Movahedi,H. Hadi,A. A. Saboury,F. Ahmad,M. Amani

Cytochrome P450 Enzymes Mechanism Based Inhibitors: Common Sub-Structures and Reactivity

Journal: Current Drug Metabolism
Volume: 6 Issue: 5 Year: 2005 Page: 413-451
Author(s): E. Fontana, P. M. Dansette, S. M. Poli

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