Search Result "ligand- and receptor-based models"


A Molecular Guidance System Based Upon Target Genes, Nuclear Receptors and Ligands Applied to Drug Discovery and Prediction of Toxicity

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1252-1264
Author(s): Virendra B. Mahesh, Neil Sidell, Douglas E. Ewing, Edwin D. Bransome Jr., Lawrence B. Hendry

Computational Analysis of the Interaction between Ligand-Receptor Pairs

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 6 Year: 2008 Page: 588-592
Author(s): Zhenran Jiang

A Ligand-Based Approach to Mining the Chemogenomic Space of Drugs

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 8 Year: 2008 Page: 669-676
Author(s): Elisabet Gregori-Puigjane, Jordi Mestres

Recent Advances in the Development of Selective Ligands for the Cannabinoid CB2 Receptor

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 3 Year: 2008 Page: 187-204
Author(s): John W. Huffman, Karla-Sue C. Marriott

Fluorescent GPCR Ligands as New Tools in Pharmacology

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2132-2143
Author(s): Kamil Kuder, Katarzyna Kiec-Kononowicz

Molecular Recognition Models: A Challenge to Overcome

Journal: Current Drug Targets
Volume: 9 Issue: 1 Year: 2008 Page: 1077-1083
Author(s): Rafael Andrade Caceres, Ivani Pauli, Luis Fernando Saraiva Macedo Timmers, Walter Filgueira de Azevedo Jr.

Computational Methods for Calculation of Ligand-Binding Affinity

Journal: Current Drug Targets
Volume: 9 Issue: 1 Year: 2008 Page: 1031-1039
Author(s): Walter Filgueira de Azevedo Jr., Raquel Dias

The Role of Natural Products in the Ligand Deorphanization of TRP Channels

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 1 Year: 2008 Page: 2-17
Author(s): G. Appendino, A. Minassi, A. Pagani, A. Ech-Chahad

Estrogen Receptor: Structural Differences and Potential Implications on Selectivity Examined by the GRID/CPCA Approach

Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 3 Year: 2008 Page: 182-192
Author(s): I. R.A. de Menezes, A. Leitao, C. A. Montanari

Bivalent Ligands as Specific Pharmacological Tools for G Protein-Coupled Receptor Dimers

Journal: Current Drug Discovery Technologies
Volume: 5 Issue: 4 Year: 2008 Page: 312-318
Author(s): Isabelle Berque-Bestel, Frank Lezoualch, Ralf Jockers

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