Search Result "lead optimization"


Methodologies to Assess Brain Drug Delivery in Lead Optimization

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2009 Page: 148-162
Author(s): Margareta Hammarlund-Udenaes, Ulf Bredberg, Markus Friden

Back to the Future: Lessons Learned in Modern Target-based and Whole-Cell Lead Optimization of Antimalarials

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 5 Year: 2012 Page: 473-483
Author(s): Arnab K. Chatterjee, Bryan K.S. Yeung

Review Article

Lead Optimization Resources in Drug Discovery for Diabetes

Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 19 Issue: 6 Year: 2019 Page: 754-774
Author(s): Pragya Tiwari,Ashish Katyal,Mohd F. Khan,Ghulam Md. Ashraf,Khurshid Ahmad

Strategy of Utilizing In Vitro and In Vivo ADME Tools for Lead Optimization and Drug Candidate Selection

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 1033-1038
Author(s): Suresh K. Balani, Gerald T. Miwa, Liang-Shang Gan, Jing-Tao Wu, Frank W. Lee

Computational Approaches for Fragment Optimization

Journal: Current Computer-Aided Drug Design
Volume: 3 Issue: 1 Year: 2007 Page: 69-83
Author(s): Eric Vangrevelinghe, Simon Rudisser

Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas

Rational Approaches Towards Lead Optimization of Kinase Inhibitors: The Issue of Specificity

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 26 Year: 2013 Page: 4714-4738
Author(s): Preethi Badrinarayan,G. Narahari Sastry

Does TheChosen Equalizer Lead To Optimal Equalization Performance?

Ebook: Young People’s Visions of the World

Volume: 1 Year: 2010
Author(s): Monika Pinchas
Doi: 10.2174/97816080535201120101

Pareto Optimality

Ebook: Multi-Objective Optimization in Theory and Practice I: Classical Methods

Volume: 1 Year: 2017
Author(s): Andre A. Keller
Doi: 10.2174/9781681085685117010005
Editorial free to download

Editorial: Computer Aided Structure-based Lead Optimization

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 23 Year: 2017 Page: 2575-2576
Author(s): Thijs Beuming,Lei Shi

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