Search Result "in vitro potency"


Building a Tiered Approach to In Vitro Predictive Toxicity Screening: A Focus on Assays with In Vivo Relevance

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 188-206
Author(s): James M. McKim Jr.

The Potency of Refined Mouse Models: Implications for Clinical Trials

Journal: Current Cancer Therapy Reviews
Volume: 6 Issue: 1 Year: 2010 Page: 62-80
Author(s): Ralph Graeser, Ulrike Fiedler, Norbert Esser, Andrea Klotzbuecher, Holger Weber, Christoph Schaechtele

Kinetic Analysis of Oxime Interactions with Acetylcholinesterase as a Basis for the Evaluation of Oxime Efficacy in Organophosphate Poisoning

Journal: Current Bioactive Compounds
Volume: 6 Issue: 1 Year: 2010 Page: 16-22
Author(s): F. Worek, P. Eyer, N. Aurbek, H. Thiermann

Lipoplexes Formulation and Optimisation: In Vitro Transfection Studies Reveal No Correlation with In Vivo Vaccination Studies

Journal: Current Drug Delivery
Volume: 7 Issue: 2 Year: 2010 Page: 175-187
Author(s): Sarah E. McNeil, Anil Vangala, Vincent W. Bramwell, Peter J. Hanson, Yvonne Perrie

Scaling In Vivo Pharmacokinetics from In Vitro Metabolic Stability Data in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 159-169
Author(s): Wendy Klopf, Philip Worboys

In Silico Ligand-Receptor Docking of Potentially Selective Butyrylcholinesterase Inhibitors Structurally Related to the Marine Natural Product Debromoflustramine B

Journal: Medicinal Chemistry
Volume: 6 Issue: 3 Year: 2010 Page: 141-143
Author(s): Miguel O. Mitchell, Robert W. Figliozzi, Mustafa Guzel

Emerging In Vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 199-222
Author(s): Cormac Concannon, Desmond A. Hennelly, Simon Noott, Dipak K. Sarker, Chuang Lu, Mingxiang Liao, Lawrence Cohen, Cindy Q. Xia

Synthesis and In Vitro Evaluation of New Tacrine Derivates-Bis-Alkylene Linked 7-MEOTA

Journal: Letters in Organic Chemistry
Volume: 7 Issue: 4 Year: 2010 Page: 327-331
Author(s): Jan Korabecny, Ondrej Holas, Kamil Musilek, Miroslav Pohanka, Veronika Opletalova, Vlastimil Dohnal, Kamil Kuca

Current In Vitro High Throughput Screening Approaches to Assess Nuclear Receptor Activation

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 806-814
Author(s): Judy L. Raucy, Jerome M. Lasker

Synthesis and In Vitro Evaluation of Some Isatin-Thiazolidinone Hybrid Analogues as Anti-Proliferative Agents

Journal: Medicinal Chemistry
Volume: 6 Issue: 5 Year: 2010 Page: 306-312
Author(s): P. K. Ramshid, Sankar Jagadeeshan, Anand Krishnan, Mary Mathew, S. Asha Nair, M. Radhakrishna Pillai

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