Search Result "in vitro potency"


Bone Targeting Prodrugs Based on Peptide Dendrimers, Synthesis and Hydroxyapatite Binding In Vitro

Journal: Letters in Organic Chemistry
Volume: 6 Issue: 4 Year: 2009 Page: 272-277
Author(s): Liang Ouyang, Wencai Huang, Gu He, Li Guo

Kv1.5 Blockers for the Treatment of Atrial Fibrillation: Approaches to Optimization of Potency and Selectivity and Translation to In Vivo Pharmacology

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 5 Year: 2009 Page: 436-451
Author(s): Mark T. Bilodeau, B. Wesley Trotter

PDE5 Inhibitors: In Vitro and In Vivo Pharmacological Profile

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 3 Year: 2009 Page: 3464-3475
Author(s): D. Kouvelas, A. Goulas, G. Papazisis, C. Sardeli, C. Pourzitaki

In Vitro Evidence for Competitive TSPO Binding of the Imaging Biomarker Candidates Vinpocetine and Two Iodinated DAA1106 Analogues in Post Mortem Autoradiography Experiments on Whole Hemisphere Human Brain Slices

Journal: Current Radiopharmaceuticals
Volume: 2 Issue: 1 Year: 2009 Page: 42-48
Author(s): Balazs Gulyas, Boglarka Makkai, Katalin Nagy, Adam Vas, Peter Kasa, Jan Andersson, Tetsuya Suhara, Kazutoshi Suzuki, Makoto Higuchi, Zsuzsa Beliczai, Karoly Gulya, Laszlo Csiba, Christer Halldin

Discovery and Development of a Potent and Highly Selective Small Molecule Muscarinic Acetylcholine Receptor Subtype I (mAChR 1 or M1) Antagonist In Vitro and In Vivo Probe

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1217-1226
Author(s): C. David Weaver, Douglas J. Sheffler, L. Michelle Lewis, Thomas M. Bridges, Richard Williams, Natalia T. Nalywajko, J. Phillip Kennedy, Matthew M. Mulder, Satyawan Jadhav, Leslie A. Aldrich, Carrie K. Jones, Joy Marlo, Colleen M. Niswender, Matthew M. Mock, Fang Zheng, P. Jeffrey Conn, Craig W. Lindsley

Disodium Phosphate of Norcantharidin Analogues: Design, Synthesis and their Anticancer Evaluation

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 5 Year: 2009 Page: 345-352
Author(s): Liping Deng, Yongmiao Shen, Wei Wang, Weifeng Tao, Jianguo Lv, Chunlei Wu

Evaluation of ISCOMs for Immunization Against Hepatitis B

Journal: Current Pharmaceutical Biotechnology
Volume: 10 Issue: 7 Year: 2009 Page: 709-716
Author(s): R. S. Pandey, V. K. Dixit

Successful Structure-Based Design of Recent p38 MAP Kinase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 7 Year: 2009 Page: 655-676
Author(s): Solveigh C. Karcher, Stefan A. Laufer

Synthesis, Structural Characterization and Antibacterial Activity of Novel 7β-{[3-(substituted phenyl)-2-propenoyl]amino}-3-[(2,5-dihydro-6-hydroxy- 2-methyl)-5-oxo-cis-triazin-3-yl]-thiomethyl-cefalosporins

Journal: Medicinal Chemistry
Volume: 5 Issue: 3 Year: 2009 Page: 283-292
Author(s): Zalua Rodriguez, Miguel A. Lopez, Maritza Gonzalez, Blanca Tolon, Loreta Nadal, Leonora Gonzalez, Herman Velez, Adamo Fini

High Throughput Quantitative Assessment of CYP Inactivation Using 2 Concentration Points

Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 78-82
Author(s): Daniel Albaugh, Thomas Farrell, Michael Langan, W. George Lai

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