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Building a Tiered Approach to In Vitro Predictive Toxicity Screening: A Focus on Assays with In Vivo Relevance

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 188-206
Author(s): James M. McKim Jr.

Application of Modern Drug Metabolism Structure Determination Tools and Assays to the In Vitro Metabolism of Imiloxan

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 77-87
Author(s): William L. Fitch, Yuan Chen, Liling Liu, Axel Paehler, May Young

Enzyme Kinetics and Hit Validation in Fluorimetric Protease Assays

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 368-382
Author(s): Stephanie Ludewig, Markus Kossner, Markus Schiller, Knut Baumann, Tanja Schirmeister

PMCA. A Decade of In Vitro Prion Replication

Journal: Current Chemical Biology
Volume: 4 Issue: 3 Year: 2010 Page: 200-207
Author(s): Natalia Fernandez-Borges, Joaquin Castilla

Membrane and Dye Efflux Assays to Detect and Characterize the Interaction of Drugs with ABC Transporters

Ebook: Young People’s Visions of the World

Volume: 1 Year: 2010
Author(s): Eniko Ioja,Zoltan Nagy,Viktoria Juhasz,Judit Janossy,Krisztina Heredi-Szabo,Peter Krajcsi
Doi: 10.2174/97816080512051110101

Lipophilic Mediated Assays for β-Hematin Inhibitors

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 3 Year: 2010 Page: 285-292
Author(s): Melissa D. Carter, Vanessa V. Phelan, Rebecca D. Sandlin, Brian O. Bachmann, David W. Wright

Current In Vitro High Throughput Screening Approaches to Assess Nuclear Receptor Activation

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 806-814
Author(s): Judy L. Raucy, Jerome M. Lasker

Identifying a Higher Throughput Assay for Metabolism Dependent Inhibition (MDI)

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 104-113
Author(s): Mahmud Kajbaf, Emiliano Palmieri, Raffaele Longhi, Stefano Fontana

Combination of Functional Cardiomyocytes Derived from Human Stem Cells and a Highly-Efficient Microelectrode Array System: An Ideal Hybrid Model Assay for Drug Development

Journal: Current Stem Cell Research & Therapy
Volume: 5 Issue: 3 Year: 2010 Page: 227-232
Author(s): Yasuyuki Asai, Masako Tada, Tomomi G. Otsuji, Norio Nakatsuji

Enzyme Induction: Translating Multiple Approaches, Assays, Endpoints, and Opinions into a Valuable Induction Screening Strategy

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 135-144
Author(s): Adrian Fretland, Mario Monshouwer

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