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Oxidative Bioactivation and Toxicity of Leflunomide in Immortalized Human Hepatocytes and Kinetics of the Non-Enzymatic to Its Major etabolitie, A77 1726

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 153-157
Author(s): Quee Ming Seah, Lee-Sun New, Eric C.Y. Chan, Urs A. Boeslsterli

Hepatocytes as Cytotoxic Effector Cells

Journal: Current Immunology Reviews
Volume: 4 Issue: 4 Year: 2008 Page: 215-220
Author(s): Clifford S. Guy, Tomasz I. Michalak

Induction of Cytochrome P450 3A by the Ginkgo biloba Extract and Bilobalides in Human and Rat Primary Hepatocytes

Journal: Drug Metabolism Letters
Volume: 2 Issue: 1 Year: 2008 Page: 60-66
Author(s): Shu-Feng Zhou, Ying Deng, Hui-chang Bi, Li-zi Zhao, Xue-ding Wang, Jie Chen, Zhi-min Ou, Liang Ding, Le-jia Xu, Su Guan, Xiao Chen, Min Huang

Assessment of Cytochrome P450 Induction in Human Hepatocytes Using the Cocktail Strategy Plus Liquid Chromatography Tandem Mass Spectrometry

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 205-209
Author(s): Agustin Lahoz, Maria Teresa Donato, Laura Picazo, Jose V. Castell, Maria Jose Gomez-Lechon

Identification of Apoptotic Drugs: Multiparametric Evaluation in Cultured Hepatocytes

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2071-2085
Author(s): Maria Jose Gomez-Lechon, Jose Enrique OConnor, Agustin Lahoz, Jose V. Castell, Maria Teresa Donato

Investigations Into the Drug-Drug Interaction Potential of Tapentadol in Human Liver Microsomes and Fresh Human Hepatocytes

Journal: Drug Metabolism Letters
Volume: 2 Issue: 1 Year: 2008 Page: 67-75
Author(s): Christa Kneip, Rolf Terlinden, Horst Beier, Genfu Chen

Aldehyde Oxidase Activity and Inhibition in Hepatocytes and Cytosolic Fraction from Mouse, Rat,Monkey and Human

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 176-183
Author(s): Jasminder Sahi, Kishore K. Khan, Chris B. Black

Quantitative Relationship Between Rifampicin Exposure and Induction of CYP3a11 in SXR Humanized Mice: Extrapolation to Human CYP3A4 Induction Potential

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 169-175
Author(s): Sean Kim, Devin Pray, Ming Zheng, Danial G. Morgan, Jenifer G. Pizzano, Mary E. Zoeckler, Anjaneya Chimalakonda, Michael W. Sinz

Cell Lines: A Tool for In Vitro Drug Metabolism Studies

Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 1-11
Author(s): M. J. Gomez-Lechon, M. T. Donato, A. Lahoz, J. V Castell

Troglitazone Thiol Adduct Formation in Human Liver Microsomes: Enzyme Knietics and Reaction Phenotyping

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 184-189
Author(s): Jinping Gan, Qinling Qu, Bing He, Wen C. Shyu, A. David Rodrigues, Kan He

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