Search Result "hit identification."


NMR Screening and Hit Validation in Fragment Based Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas

Proteolytic Cleavage of Notch: “HIT and RUN”

Journal: Current Molecular Medicine
Volume: 11 Issue: 4 Year: 2011 Page: 255-269
Author(s): G. van Tetering, M. Vooijs

Ligand and Structure Based Virtual Screening Strategies for Hit-Finding and Optimization of Hepatitis C Virus (HCV) Inhibitors

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2612-2619
Author(s): G. Melagraki, A. Afantitis

Identification of Plant Protein Kinases in Response to Abiotic and Biotic Stresses Using SuperSAGE

Journal: Current Protein & Peptide Science
Volume: 12 Issue: 7 Year: 2011 Page: 643-656
Author(s): Ederson Akio Kido, Pedranne Kelle de Araujo Barbosa, Jose Ribamar Costa Ferreira Neto, Valesca Pandolfi, Laureen Michelle Houllou-Kido, Sergio Crovella, Carlos Molina, Gunter Kahl, Ana Maria Benko-Iseppon

Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1284-1291
Author(s): Ian H. Gilbert, Didier Leroy, Julie A. Frearson

Drug Design of GPCR Ligands Using Physicogenetics and Chemogenomics - Principles and Case Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1882-1901
Author(s): Thomas M. Frimurer, Thomas Hogberg

Thematic Analysis™ : A Chemogenomic Approach to GPCR Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1925-1943
Author(s): Roger Crossley, Jacqueline Anne Macritchie, Martin John Slater

Integration of Virtual and High Throughput Screening in Lead Discovery Settings

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 1 Year: 2011 Page: 889-897
Author(s): Timea Polgar, Gyorgy M. Keseru

Identification and Characterization of mGlu3 Ligands Using a High Throughput FLIPR Assay for Detection of Agonists, Antagonists, and Allosteric Modulators

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 7 Year: 2011 Page: 631-641
Author(s): Steven D. Pratt, Mario Mezler, Herve Geneste, Margot H.M. Bakker, Philip J. Hajduk, Sujatha M. Gopalakrishnan

Modern Drug Discovery Technologies: Opportunities and Challenges in Lead Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 1 Year: 2011 Page: 830-839
Author(s): Rafael V. C. Guido, Glaucius Oliva, Adriano D. Andricopulo

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