Search Result "hERG screening"


Tuning hERG Out: Antitarget QSAR Models for Drug Development

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1399-1415
Author(s): Rodolpho C. Braga,Vinicius M. Alves,Meryck F.B. Silva,Eugene Muratov,Denis Fourches,Alexander Tropsha,Carolina H. Andrade

Scaffold Hopping for Identification of Novel PKCβII Inhibitors Based on Ligand and Structural Approaches, Virtual Screening and Molecular Dynamics Study

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 1 Year: 2014 Page: 2-11
Author(s): Baljinder K. Grewal,Masilamani E. Sobhia

Biologically Active Ligands for Yersinia Outer Protein H (YopH): Feature Based Pharmacophore Screening, Docking and Molecular Dynamics Studies

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 7 Year: 2014 Page: 579-595
Author(s): Thangaraju Tamilvanan,Waheeta Hopper

Discovery of Aroyl Piperazine Derivatives as IKr & IKs Dual Inhibitors for Cardiac Arrhythmia Treatment

Journal: Medicinal Chemistry
Volume: 10 Issue: 5 Year: 2014 Page: 497-505
Author(s): Xiaoke Guo,Haopeng Sun,Lvpei Du,Lu Huang,Jing Xu,Yingying Zhu,Peng Yu,Xiaojin Zhang,Yiqun Tang,Qidong You

Mycobacterial DNA GyrB Inhibitors: Ligand Based Pharmacophore Modelling and In Vitro Enzyme Inhibition Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 17 Year: 2014 Page: 1990-2005
Author(s): Shalini Saxena,Janupally Renuka,Variam Ullas Jeankumar,Perumal Yogeeswari,Dharmarajan Sriram

Zebrafish Model in Drug Safety Assessment

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 34 Year: 2014 Page: 5416-5429
Author(s): Jyotshna Kanungo,Elvis Cuevas,Syed F. Ali,Merle G. Paule

Recent Development of CB2 Selective and Peripheral CB1/CB2 Cannabinoid Receptor Ligands

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 2 Year: 2014 Page: 187-203
Author(s): Tapio Nevalainen

Structure-Based Drug Design of Novel MARK-3 Inhibitors in Cancer

Journal: Current Bioactive Compounds
Volume: 10 Issue: 2 Year: 2014 Page: 131-138
Author(s): Josiana G. de Araujo Volpini,Ricardo P. Rodrigues,Leonardo B. Federico,Carlos H.T. de Paula da Silva

Prospects for Developing New Antibacterials Targeting Bacterial Type IIA Topoisomerases

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 1 Year: 2014 Page: 130-151
Author(s): Tihomir Tomašić,Lucija Peterlin Mašič

Open Innovation Drug Discovery (OIDD): A Potential Path to Novel Therapeutic Chemical Space

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 3 Year: 2014 Page: 294-303
Author(s): Maria Alvim-Gaston, Timothy Grese, Abdelaziz Mahoui, Alan D. Palkowitz, Marta Pineiro-Nunez, Ian Watson

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