Search Result "hERG screening"


In Silico Predictions of hERG Channel Blockers in Drug Discovery: From Ligand-Based and Target-Based Approaches to Systems Chemical Biology

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 5 Year: 2011 Page: 375-387
Author(s): Olivier Taboureau, Flemming Steen Jorgensen

QSAR and Pharmacophore Analysis of a Series of Piperidinyl Urea Derivatives as hERG Blockers and H3 Antagonists

Journal: Current Drug Discovery Technologies
Volume: 10 Issue: 1 Year: 2013 Page: 47-58
Author(s): N. S. Hari Narayana Moorthy, Maria J. Ramos, Pedro A. Fernandes

Ion Channel Screening

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 7 Year: 2008 Page: 514-522
Author(s): John Dunlop, Mark Bowlby, Ravikumar Peri, Gregory Tawa, James LaRocque, Veronica Soloveva, John Morin

Port-a-Patch and Patchliner: High Fidelity Electrophysiology for Secondary Screening and Safety Pharmacology

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 1 Year: 2009 Page: 24-37
Author(s): Niels Fertig, Andrea Bruggemann, Mohamed Kreir, Michael George, Sonja Stoelzle, Claudia Haarmann, Cecilia Farre, Alison Haythornthwaite

Essential Factors for Successful Virtual Screening

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 63-72
Author(s): Markus H.J. Seifert, Martin Lang

Ion Channel Screening Technology

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7 Issue: 2 Year: 2008 Page: 122-128
Author(s): Michael A. Dabrowski, Kim Dekermendjian, Per-Eric Lund, Johannes J. Krupp, Jon Sinclair, Olof Larsson

Insights into the Molecular Mechanism of hERG1 Channel Activation and Blockade by Drugs

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 3514-3532
Author(s): S. Durdagi, J. Subbotina, J. Lees-Miller, J. Guo, H. J. Duff, S. Y. Noskov

Exploiting High-Throughput Ion Channel Screening Technologies in Integrated Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 4 Year: 2006 Page: 397-406
Author(s): J. M. Treherne

Pharmacophore Modeling for Antitargets

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 9 Year: 2013 Page: 1002-1014
Author(s): Khac-Minh Thai, Trieu-Du Ngo, Thanh-Dao Tran, Minh-Tri Le

Human Ether-a-Go-Go-Related Gene Channel Blockers and its Structural Analysis for Drug Design

Journal: Current Drug Targets
Volume: 14 Issue: 1 Year: 2013 Page: 102-113
Author(s): N. S. Hari Narayana Moorthy,Maria J. Ramos,Pedro A. Fernandes

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