Search Result "fragment discovery"


Probing a Chemical Space for Fragmental Topology-Activity Landscapes (FRAGTAL): Application for Diketo Acid and Catechol HIV Integrase Inhibitor Offspring Fragments

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 16 Issue: 4 Year: 2013 Page: 274-287
Author(s): Andrzej Bak,Tomasz Magdziarz,Agata Kurczyk,Katarzyna Serafin,Jaroslaw Polanski

From Small to Powerful: The Fragments Universe and its “Chem-Appeal”

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1355-1381
Author(s): Luca Sancineto, Serena Massari, Nunzio Iraci, Oriana Tabarrini

Multi-Target Inhibitors for Proteins Associated with Alzheimer: In Silico Discovery using Fragment-Based Descriptors

Journal: Current Alzheimer Research
Volume: 10 Issue: 2 Year: 2013 Page: 117-124
Author(s): Alejandro Speck-Planche,Valeria V. Kleandrova,Feng Luan,M. Natalia D. S. Cordeiro

Predicting Targeted Polypharmacology for Drug Repositioning and Multi- Target Drug Discovery

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1646-1661
Author(s): X. Liu, F. Zhu, X. H. Ma, Z. Shi, S. Y. Yang, Y. Q. Wei, Y. Z. Chen

X-ray Crystallography and Computational Docking for the Detection and Development of Protein–Ligand Interactions

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 4 Year: 2013 Page: 569-575
Author(s): N.M. Kershaw,G.S.A. Wright,R. Sharma,S.V. Antonyuk,R.W. Strange,N.G. Berry,P.M. O'Neill,S.S. Hasnain

Comprehensive Profiling of Protein Ubiquitination for Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 1 Year: 2013 Page: 3315-3328
Author(s): Guoqiang Xu, Samie R. Jaffrey

Pharmacokinetic Properties and In Silico ADME Modeling in Drug Discovery

Journal: Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2013 Page: 163-176
Author(s): Kathia M. Honorio,Tiago L. Moda,Adriano D. Andricopulo

Synthesis of New Compounds Combining Adamantanamine and Monoterpene Fragments and their Antiviral Activity Against Influenza Virus A(H1N1)pdm09

Journal: Letters in Drug Design & Discovery
Volume: 10 Issue: 6 Year: 2013 Page: 477-485
Author(s): George V. Teplov, Evgeny V. Suslov, Vladimir V. Zarubaev, Anna A. Shtro, Liubov A. Karpinskaya, Artem D. Rogachev, Dina V. Korchagina, Konstantin P. Volcho, Nariman F. Salakhutdinov, Oleg I. Kiselev

Review Article

Virtual Screening Strategies in Drug Discovery: A Critical Review

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 23 Year: 2013 Page: 2839-2860
Author(s): A. Lavecchia,C. Di Giovanni

Metabolomics Analysis for Biomarker Discovery: Advances and Challenges

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 2 Year: 2013 Page: 257-271
Author(s): M.S. Monteiro,M. Carvalho,M.L. Bastos,P. Guedes de Pinho

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