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Enzyme Kinetics and Hit Validation in Fluorimetric Protease Assays

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 368-382
Author(s): Stephanie Ludewig, Markus Kossner, Markus Schiller, Knut Baumann, Tanja Schirmeister

Identifying a Higher Throughput Assay for Metabolism Dependent Inhibition (MDI)

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 104-113
Author(s): Mahmud Kajbaf, Emiliano Palmieri, Raffaele Longhi, Stefano Fontana

Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes

Journal: Current Signal Transduction Therapy
Volume: 5 Issue: 1 Year: 2010 Page: 74-91
Author(s): Tracey M. Gloster, David J. Vocadlo

Evaluation of Cytochrome P450 Inhibition Assays Using Human Liver Microsomes by a Cassette Analysis /LC-MS/MS

Journal: Drug Metabolism Letters
Volume: 4 Issue: 3 Year: 2010 Page: 120-128
Author(s): Serenella Zambon, Stefano Fontana, Mahmud Kajbaf

Homodimeric Enzymes as Drug Targets

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 9 Year: 2010 Page: 826-846
Author(s): D. Cardinale, O. M.H. Salo-Ahen, S. Ferrari, G. Ponterini, G. Cruciani, E. Carosati, A. M. Tochowicz, S. Mangani, R. C. Wade, M. P. Costi

Enzyme Induction: Translating Multiple Approaches, Assays, Endpoints, and Opinions into a Valuable Induction Screening Strategy

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 135-144
Author(s): Adrian Fretland, Mario Monshouwer

Development of Enzyme-Linked Immunosorbent Assay System for PEDF and its Clinical Utility

Journal: Current Molecular Medicine
Volume: 10 Issue: 3 Year: 2010 Page: 317-320
Author(s): K. Fukami, S.-I. Yamagishi, S. Okuda

Enzyme Inhibition as a Key Target for the Development of Novel Metal-Based Anti-Cancer Therapeutics

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10 Issue: 5 Year: 2010 Page: 354-370
Author(s): Darren Griffith, James P. Parker, Celine J. Marmion

A Universal, Fully Automated High Throughput Screening Assay for Pyrophosphate and Phosphate Release from Enzymatic Reactions

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 1 Year: 2010 Page: 27-38
Author(s): Scott D. Pegan, Yang Tian, Valerie Sershon, Andrew D. Mesecar

Coupling the Inhibition of Viral Transduction with a Positive Fluorescence Signal

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 4 Year: 2010 Page: 352-357
Author(s): Jenifer Clausell-Tormos, Andrew D. Griffiths, Christoph A. Merten

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