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Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

Maximal Inhibition of Intestinal First-Pass Metabolism as a Pragmatic Indicator of Intestinal Contribution to the Drug-Drug Interactions for CYP3A4 Cleared Drugs

Journal: Current Drug Metabolism
Volume: 8 Issue: 7 Year: 2007 Page: 685-693
Author(s): Aleksandra Galetin, Laura K. Hinton, Howard Burt, R. Scott Obach, J. Brian Houston

An Estimate of the Number of Hepatocyte Donors Required to Provide Reasonable Estimates of Human Hepatic Clearance from In Vitro Experiments

Journal: Drug Metabolism Letters
Volume: 1 Issue: 2 Year: 2007 Page: 91-95
Author(s): James Byers, Kenneth Bachmann, Heather Eng, Anand Katta, Donald White, Ritwik Ghosh, Nicola J. Hewitt, Paul Silber, Genfu Chen

The Tumor Necrosis Factor-Derived TIP Peptide: A Potential Anti-Edema Drug

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 5 Year: 2007 Page: 336-340
Author(s): Rudolf Lucas, Harald Hundsberger, Maren Pfluger, Bernhard Fischer, Denis Morel, Clemens Braun, Albrecht Wendel, Trinad Chakraborty, Wolfgang Schutt, Christoph Wiesner, Jurg Hamacher

Molecular Mechanisms of Cytochrome P450 Induction: Potential for Drug-Drug Interactions

Journal: Current Protein & Peptide Science
Volume: 8 Issue: 6 Year: 2007 Page: 619-628
Author(s): Snehasis Jana, Jyoti Paliwal

Radioactive Drugs in Drug Development Research: Quality Assurance Issues

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 3 Year: 2007 Page: 231-244
Author(s): J. Baranowska-Kortylewicz

Stomach Specific Anti-Helicobacter Pylori Therapy: Preparation and Evaluation of Amoxicillin-Loaded Chitosan Mucoadhesive Microspheres

Journal: Current Drug Delivery
Volume: 4 Issue: 1 Year: 2007 Page: 41-50
Author(s): Jayvadan K. Patel, Madhabhai M. Patel

ABC Drug Transporters as Molecular Targets for the Prevention of Multidrug Resistance and Drug-Drug Interactions

Journal: Current Drug Delivery
Volume: 4 Issue: 4 Year: 2007 Page: 324-333
Author(s): Anna Maria Calcagno, In-Wha Kim, Chung-Pu Wu, Suneet Shukla, Suresh V. Ambudkar

Drug-Drug Interactions via Mechanism-Based Cytochrome P450 Inactivation: Points to Consider for Risk Assessment from In Vitro Data and Clinical Pharmacologic Evaluation

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 449-462
Author(s): Karthik Venkatakrishnan, R. Scott Obach

Isoprenoid Biosynthesis of the Apicoplast as Drug Target

Journal: Current Drug Targets
Volume: 8 Issue: 1 Year: 2007 Page: 3-13
Author(s): Jochen Wiesner, Hassan Jomaa

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