Search Result "blockers and activators of hERG"


Ligand Structural Aspects of hERG Channel Blockade

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1113-1127
Author(s): Alex M. Aronov

hERG (KCNH2 or Kv11.1) K+ Channels: Screening for Cardiac Arrhythmia Risk

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 965-970
Author(s): Mark R. Bowlby, Ravi Peri, Howard Zhang, John Dunlop

The hERG Channel and Risk of Drug-Acquired Cardiac Arrhythmia: An Overview

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1102-1112
Author(s): Armando A. Lagrutta, Elena S. Trepakova, Joseph J. Salata

Overcoming hERG Affinity in the Discovery of Maraviroc; A CCR5 Antagonist for the Treatment of HIV

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1140-1151
Author(s): David A. Price, Duncan Armour, Marcel de Groot, Derek Leishman, Carolyn Napier, Manos Perros, Blanda L. Stammen, Anthony Wood

The Impact of IKr Blockade on Medicinal Chemistry Programs

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1128-1139
Author(s): Ian M. Bell, Mark T. Bilodeau

Strategies for the Design of Selective Protein Kinase Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1291-1297
Author(s): Masaaki Sawa

Editorial [Hot topic: Medicinal Chemistry Strategies to Minimize hERG Channel Effects 23 May (Guest Editor:Mark T. Bilodeau)]

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1101-1101
Author(s): Mark T. Bilodeau

Targeting Potassium Channels: New Advances in Cardiovascular Therapy

Journal: Recent Patents on Cardiovascular Drug Discovery (Discontinued)
Volume: 3 Issue: 2 Year: 2008 Page: 105-118
Author(s): Ramon Martinez-Marmol, Meritxell Roura-Ferrer, Antonio Felipe

Melanin-Concentrating Hormone Receptor 1 Antagonists: A New Perspective for the Pharmacologic Treatment of Obesity

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1025-1043
Author(s): Gildardo Rivera, Virgilio Bocanegra-Garcia, Silvia Galiano, Nuria Cirauqui, Javier Ceras, Silvia Perez, Ignacio Aldana, Antonio Monge

Ion Channel Screening

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 7 Year: 2008 Page: 514-522
Author(s): John Dunlop, Mark Bowlby, Ravikumar Peri, Gregory Tawa, James LaRocque, Veronica Soloveva, John Morin

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