Search Result "bioisosterism"


Synthesis, Antibacterial Activity of 2,4-Disubstituted Oxazoles and Thiazoles as Bioisosteres

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 1 Year: 2009 Page: 21-28
Author(s): Mohamed Kaspady, Venugopala Katharigatta Narayanaswamy, Mohana Raju, Gopal Krishna Rao

Syntheses of Ethyl Pyruvate’s Bioisosteres Inhibiting Inducible Nitric Oxide Production in Lipopolysaccharide-induced BV2 Cells

Journal: Letters in Drug Design & Discovery
Volume: 12 Issue: 7 Year: 2015 Page: 591-596
Author(s): Ju-Young Park,Byung-Wook Kim,Soon-Jung Kwon,Dong-Kug Choi,Ja-Kyeong Lee,Sung-Hwa Yoon

In Silico Techniques for the Identification of Bioisosteric Replacements for Drug Design

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 6 Year: 2010 Page: 657-668
Author(s): Mike Devereux, Paul L.A. Popelier

Synthesis and Biological Evaluation of Novel Bioisosteric Analogues of Dimebon™

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 6 Year: 2010 Page: 446-451
Author(s): Alexandre Vasilevich Ivachtchenko, Eugene Borisovich Frolov, Oleg Dmitrievich Mitkin, Sergey Evgenevich Tkachenko, Alexandre Khvat

In Silico Bioisosteric Replacements of hnRNP K Ligands as Anticancer Lead Compounds

Journal: Current Physical Chemistry
Volume: 4 Issue: 1 Year: 2014 Page: 30-34
Author(s): Vinicius B. Da Silva,Andreia M. Leopoldino,Carlos H.T.P. Da Silva

Synthesis, Characterization, Biological Evaluation and Docking of Coumarin Coupled Thiazolidinedione Derivatives and its Bioisosteres as PPARγ Agonists

Journal: Medicinal Chemistry
Volume: 8 Issue: 5 Year: 2012 Page: 834-845
Author(s): Shubhanjali Shukla,Pankaj Kumar,Nirupam Das,N.S. Hari Narayana Moorthy,Sushant Kumar Shrivastava,Piyush Trivedi,Radhey Shyam Srivastava

Syntheses of 2,3-Dihydro-1,4-Benzodioxins and Bioisosteres as Structural Motifs for Biologically Active Compounds

Journal: Current Organic Chemistry
Volume: 15 Issue: 6 Year: 2011 Page: 869-887
Author(s): Olga Cruz-Lopez, Maria C. Nunez, Ana Conejo-Garcia, Maria Kimatrai, Joaquin M. Campos

Research Article

Bioisosteric Replacement and Related Analogs in the Design, Synthesis and Evaluation of Ligands for Muscarinic Acetylcholine Receptors

Journal: Medicinal Chemistry
Volume: 10 Issue: 4 Year: 2014 Page: 361-375
Author(s): Richie R. Bhandare,Daniel J. Canney

QSAR and Molecular Docking Techniques for the Discovery of Potent Monoamine Oxidase B Inhibitors: Computer-Aided Generation of New Rasagiline Bioisosteres

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 16 Year: 2012 Page: 1734-1747
Author(s): Alejandro Speck-Planche,Valeria V. Kleandrova

Synthesis and Biological Evaluation of 2-amino-3-(3, 4, 5-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a New Class of Antitubulin Agents

Journal: Medicinal Chemistry
Volume: 3 Issue: 6 Year: 2007 Page: 507-512
Author(s): Romeo Romagnoli, Pier Giovanni Baraldi, Vincent Remusat, Maria Dora Carrion, Carlota Lopez Cara, Olga Cruz-Lopez, Delia Preti, Francesca Fruttarolo, Mojgan Aghazadeh Tabrizi, Jan Balzarini, Ernest Hamel

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