Search Result "amyloid-�� protein precursor"


Research Article

Amyloid Precursor Protein Knockout Diminishes Synaptic Vesicle Proteins at the Presynaptic Active Zone in Mouse Brain

Journal: Current Alzheimer Research
Volume: 11 Issue: 10 Year: 2014 Page: 971-980
Author(s): Melanie Laßek,Jens Weingarten,Amparo Acker-Palmer,Sandra M. Bajjalieh,Ulrike Muller,Walter Volknandt

Effect of Trichostatin A on Gelsolin Levels, Proteolysis of Amyloid Precursor Protein, and Amyloid Beta-Protein Load in the Brain of Transgenic Mouse Model of Alzheimer's Disease

Journal: Current Alzheimer Research
Volume: 11 Issue: 10 Year: 2014 Page: 1002-1011
Author(s): Wenzhong Yang,Abha Chauhan,Jerzy Wegiel,Izabela Kuchna,Feng Gu,Ved Chauhan

The Intracellular Domain of Amyloid Precursor Protein is a Potential Therapeutic Target in Alzheimer’s Disease

Journal: Current Drug Discovery Technologies
Volume: 11 Issue: 4 Year: 2014 Page: 243-258
Author(s): Hisashi Nagase,Kohzo Nakayama

Fetzima (levomilnacipran), a Drug for Major Depressive Disorder as a Dual Inhibitor for Human Serotonin Transporters and Beta-Site Amyloid Precursor Protein Cleaving Enzyme-1

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13 Issue: 8 Year: 2014 Page: 1427-1431
Author(s): Syed Mohd. Danish Rizvi,Sibhghatulla Shaikh,Mahiuddin Khan,Deboshree Biswas,Nida Hameed,Shazi Shakil

Screening for Amyloid Aggregation: In-Silico, In-Vitro and In-Vivo Detection

Journal: Current Protein & Peptide Science
Volume: 15 Issue: 5 Year: 2014 Page: 477-489
Author(s): Anna Villar-Pique,Alba Espargaro,Salvador Ventura,Raimon Sabate

Dangerous Liaisons between Beta-Amyloid and Cholinergic Neurotransmission

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 1 Year: 2014 Page: 2525-2538
Author(s): Stefano Govoni, Elisa Mura, Stefania Preda, Marco Racchi, Cristina Lanni, Massimo Grilli, Stefania Zappettini, Alessia Salamone, Guendalina Olivero, Anna Pittaluga, Mario Marchi

Accumulation of Intraneuronal Amyloid-β is Common in Normal Brain

Journal: Current Alzheimer Research
Volume: 11 Issue: 4 Year: 2014 Page: 317-324
Author(s): Jeffrey A. Blair, Sandra L. Siedlak, Julie A. Wolfram, Akihiko Nunomura, Rudy J. Castellani, Sergio T. Ferreira, William L. Klein, Yang Wang, Gemma Casadesus, Mark A. Smith, George Perry, Xiongwei Zhu, Hyoung-gon Lee

Pomegranate Extract Modulates Processing of Amyloid-β Precursor Protein in an Aged Alzheimer`s Disease Animal Model

Journal: Current Alzheimer Research
Volume: 11 Issue: 9 Year: 2014 Page: 834-843
Author(s): Aseef H. Ahmed, Gehad M. Subaiea, Aseel Eid, Liya Li, Navindra P. Seeram, Nasser H. Zawia

Clearance of Beta-Amyloid in the Brain

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 35 Year: 2014 Page: 4085-4090
Author(s): Masaki Ueno,Yoichi Chiba,Koichi Matsumoto,Toshitaka Nakagawa,Hiroshi Miyanaka

Therapeutic Perspectives of Drugs Targeting Toll-Like Receptors Based on Immune Physiopathology Theory of Alzheimers Disease

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13 Issue: 5 Year: 2014 Page: 909-920
Author(s): Andrew R. Schneider,Youssef Sari

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