Search Result "allosteric modulators"


Review Article

Potential for the Rational Design of Allosteric Modulators of Class C GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 71-78
Author(s): John A. Christopher,Andrew S. Doré,Benjamin G. Tehan

Review Article

Expanding the Opportunities for Modulating Kinase Targets with Allosteric Approaches

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 59-70
Author(s): Henrik Mobitz,Wolfgang Jahnke,Sandra W. Cowan-Jacob

Research Article

Levamisole: A Positive Allosteric Modulator for the ?3?4 Nicotinic Acetylcholine Receptors Prevents Weight Gain in the CD-1 Mice on a High Fat Diet

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 1 Year: 2017 Page: 1869-1872
Author(s): Jeanne A. Lewis,Jerrel L. Yakel,Anshul A. Pandya

Review Article

Leveraging Structural Diversity and Allosteric Regulatory Mechanisms of Protein Kinases in the Discovery of Small Molecule Inhibitors

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 4 Year: 2017 Page: 4838-4872
Author(s): Gennady M. Verkhivker

Review Article

Therapeutic Modulation of Glutamate Receptors in Major Depressive Disorder

Journal: Current Neuropharmacology
Volume: 15 Issue: 1 Year: 2017 Page: 57-70
Author(s): Brittany A. Jaso, Mark J. Niciu, Nicolas D. Iadarola, Niall Lally, Erica M. Richards, Minkyung Park, Elizabeth D. Ballard, Allison C. Nugent, Rodrigo Machado-Vieira, Carlos A. Zarate

Review Article

Computer Simulations of the Retinoid X Receptor: Conformational Dynamics and Allosteric Networks

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 6 Year: 2017 Page: 731-741
Author(s): Arjan van der Vaart,Alexander Lorkowski,Ning Ma,Geoffrey M. Gray

Elucidating Allosteric Communications in Proteins via Computational Methods

Ebook: Frontiers in Computational Chemistry

Volume: 3 Year: 2017
Author(s): Burak Alakent,Z. Nevin Gerek Ince
Doi: 10.2174/9781681081670117030006
Review Article

Modulation of GABAA Receptors in the Treatment of Epilepsy

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 3 Year: 2017 Page: 5563-5568
Author(s): Eleonora Palma,Gabriele Ruffolo,Pierangelo Cifelli,Cristina Roseti,Erwin A. van Vliet,Eleonora Aronica

Review Article

Non-peptide CRF-Receptor Antagonists: Allosterism, Kinetics and Translation to Efficacy in Human Disease

Journal: Current Molecular Pharmacology
Volume: 10 Issue: 4 Year: 2017 Page: 282-295
Author(s): Samuel R.J. Hoare,Dimitri E. Grigoriadis

Research Article

Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for Modulating Pain-evoked Activities of Neurons in the Hippocampal CA3 Region of Rats

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 16 Issue: 5 Year: 2017 Page: 610-616
Author(s): Xinya Wei,Dongxiao Yang,Tiefeng Shi,Jianing Wang,Yunling Deng,Xuezhu Qiao,Chunxiao Yang,Manying Xu

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