Search Result "Trinucleotide repeats."


Analysis of the Fragile X Trinucleotide Repeat in Basques: Association of Premutation and Intermediate Sizes, Anchoring AGGs and Linked Microsatellites with Unstable Alleles

Journal: Current Genomics
Volume: 9 Issue: 3 Year: 2008 Page: 191-199
Author(s): M. I. Arrieta, J. M. Ramirez, M. Telez, P. Flores, B. Criado, M. Barasoain, I. Huerta, A. J. Gonzalez

Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene

Journal: Current Genomics
Volume: 9 Issue: 8 Year: 2008 Page: 509-516
Author(s): Beatriz Llamusi, Ruben Artero

Molecular Genetics and Biomarkers of Polyglutamine Diseases

Journal: Current Molecular Medicine
Volume: 8 Issue: 3 Year: 2008 Page: 221-234
Author(s): Masahisa Katsuno, Haruhiko Banno, Keisuke Suzuki, Yu Takeuchi, Motoshi Kawashima, Fumiaki Tanaka, Hiroaki Adachi, Gen Sobue

A Critical Evaluation of Adenosine A2A Receptors as Potentially “Druggable” Targets in Huntingtons Disease

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 1 Year: 2008 Page: 1500-1511
Author(s): Patrizia Popoli, David Blum, Maria Rosaria Domenici, Sylvie Burnouf, Yijuang Chern

New Targets for Therapy in Polyglutamine (polyQ) Expansion Diseases

Journal: Current Drug Therapy
Volume: 3 Issue: 3 Year: 2008 Page: 177-189
Author(s): Lorena Perrone, Mariarosa A.B. Melone

Neuropsychiatric and Cognitive Symptoms in Spinocerebellar Ataxia: Relationship to Neuropathological Differences

Journal: Current Psychiatry Reviews
Volume: 4 Issue: 3 Year: 2008 Page: 157-161
Author(s): Aaron M. McMurtray, Erin Saito, Susan Perlman

Conformational Changes and Aggregation of Expanded Polyglutamine Proteins as Therapeutic Targets of the Polyglutamine Diseases: Exposed β-Sheet Hypothesis

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 3 Year: 2008 Page: 3267-3279
Author(s): Yoshitaka Nagai, H. Akiko Popiel

Differential Splicing, Disease and Drug Targets

Journal: Infectious Disorders - Drug Targets
Volume: 8 Issue: 4 Year: 2008 Page: 241-251
Author(s): O. Villate, A. Rastrojo, R. Lopez-Diez, F. Hernandez-Torres, B. Aguado

Congeners of the Enediyne Neocarzinostatin Chromophore: Designed Agents for bulged Nucleic Acid Targets

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 6 Year: 2008 Page: 436-447
Author(s): Graham B. Jones, Yiqing Lin, Dong Ma, Ziwei Xiao, Geum-Sook Hwang, Lizzy Kappen, Irving H. Goldberg

Molecular Insights and Therapeutic Targets in Amyotrophic Lateral Sclerosis

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7 Issue: 1 Year: 2008 Page: 11-19
Author(s): Ammar Al-Chalabi, Vineeta B. Tripathi

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