Search Result "Topoisomerase"


Synthesis of 4-amino-5-cyano-2, 6-Disubstituted Pyrimidines as a Potential Antifilarial DNA Topoisomerase II Inhibitors

Journal: Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2008 Page: 577-585
Author(s): Ashok Kumar, J. K. Saxena, Prem M.S. Chauhan

Characterizing the Bi-Subunit Type IB DNA Topoisomerase of Leishmania Parasites; a Novel Scenario for Drug Intervention in Trypanosomatids

Journal: Current Drug Targets
Volume: 9 Issue: 1 Year: 2008 Page: 966-978
Author(s): Rosa M. Reguera, Rosario Diaz-Gonzalez, Yolanda Perez-Pertejo, Rafael Balana-Fouce

Polynucleotide Kinase as a Potential Target for Enhancing Cytotoxicity by Ionizing Radiation and Topoisomerase I Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 4 Year: 2008 Page: 358-367
Author(s): N. K. Bernstein, F. Karimi-Busheri, A. Rasouli-Nia, R. Mani, G. Dianov, J. N.M. Glover, M. Weinfeld

Kinetoplast as a Potential Chemotherapeutic Target of Trypanosomatids

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 9 Year: 2008 Page: 847-854
Author(s): Maria Cristina Machado Motta

CRM1-Mediated Nuclear Export of Proteins and Drug Resistance in Cancer

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2648-2655
Author(s): Joel G. Turner, Daniel M. Sullivan

Natural Products as Inhibitors of DNA Related Enzymes

Journal: Current Enzyme Inhibition
Volume: 4 Issue: 4 Year: 2008 Page: 194-215
Author(s): Carlos R. Pungitore

Mitochondrion of Protozoan Parasite Emerges as Potent Therapeutic Target:Exciting Drugs are on the Horizon

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 9 Year: 2008 Page: 839-846
Author(s): Nilkantha Sen, Hemanta K. Majumder

Pyrrolocarbazoles as Checkpoint 1 Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 6 Year: 2008 Page: 577-597
Author(s): Helene Henon, Elisabeth Conchon, Bernadette Hugon, Samir Messaoudi, Roy M. Golsteyn, Michelle Prudhomme

Structural Characterization, Biological Effects, and Synthetic Studies on Xanthones from Mangosteen (Garcinia mangostana), a Popular Botanical Dietary Supplement

Journal: Mini-Reviews in Organic Chemistry
Volume: 5 Issue: 4 Year: 2008 Page: 355-364
Author(s): Young-Won Chin, A. Douglas Kinghorn

Tyrosyl-DNA Phosphodiesterase as a Target for Anticancer Therapy

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 4 Year: 2008 Page: 381-389
Author(s): Thomas S. Dexheimer, Smitha Antony, Christophe Marchand, Yves Pommier

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