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Search Result "Pim Inhibitors"

Review Article

Abnormal Signal Transduction via Over-expression of Pim-1 Regulated Senescence, Cell Cycle, Apoptosis and Metastatic Invasion: Novel Anticancer Targets and Their Potent Inhibitors from Marine Sources

Journal: Current Signal Transduction Therapy
Volume: 15 Issue: 1 Year: 2020 Page: 3-11
Author(s): Ankita Sharma,Sisir Nandi

Research Article

Synthesis of Thiazole, Thiophene, Pyran and Pyridine Derivatives Derived from 3-phenyl-1H-pyrazol-5(4H)-one with Anti-proliferative, Tyrosine Kinase and PIM-1 Kinase Inhibitions

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 4 Year: 2020 Page: 484-500
Author(s): Rafat Milad Mohareb,Ibram Refat Mikhail

Review Article

Carbazole Derivatives as Kinase-Targeting Inhibitors for Cancer Treatment

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 20 Issue: 6 Year: 2020 Page: 444-465
Author(s): Jessica Ceramella,Domenico Iacopetta,Alexia Barbarossa,Anna Caruso,Fedora Grande,Maria Grazia Bonomo,Annaluisa Mariconda,Pasquale Longo,Saturnino Carmela,Maria Stefania Sinicropi Stefania Sinicropi

Review Article

Studies on Structures and Functions of Kinases leading to Prostate Cancer and Their Inhibitors

Journal: Current Enzyme Inhibition
Volume: 16 Issue: 1 Year: 2020 Page: 90-105
Author(s): Anantha Naik Nagappa,Shvetank Bhatt,Jovita Kanoujia

Research Article

Heterocyclization of 2-(2-phenylhydrazono)cyclohexane-1,3-dione to Synthesis Thiophene, Pyrazole and 1,2,4-triazine Derivatives with Anti-Tumor and Tyrosine Kinase Inhibitions

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2020 Page: 1209-1220
Author(s): Rafat M. Mohareb,Ensaf S. Alwan

Research Article

Uses of Cyclohexan-1,3-dione for the Synthesis of Thiazole, Pyrazole, Thiophene, Isoxazole and Pyran Derivatives with Antitumor Activities

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 5 Year: 2020 Page: 595-607
Author(s): Rafat Milad Mohareb,Nadia Youssef Megally Abdo,Waleed Nabeel Al-darkazali

Research Article

Investigation of Binding Characteristics of Phosphoinositide-dependent Kinase-1 (PDK1) Co-crystallized Ligands Through Virtual Pharmacophore Modeling Leading to Novel anti – PDK1 Hits

Journal: Medicinal Chemistry
Volume: 16 Issue: 7 Year: 2020 Page: 860-880
Author(s): Iman A. Mansi,Mahmoud A. Al-Sha`er,Nizar M. Mhaidat,Mutasem O. Taha,Rand Shahin

Review Article

RNA Splicing: Basic Aspects Underlie Antitumor Targeting

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 15 Issue: 4 Year: 2020 Page: 293-305
Author(s): Alzahraa A.M. Fergany,Victor V. Tatarskiy

Research Article

Design and Synthesis of New Substituted Pyrazolopyridines with Potent Antiproliferative Activity

Journal: Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2020 Page: 176-191
Author(s): Vassiliki Giannouli,Nikolaos Lougiakis,Ioannis K. Kostakis,Nicole Pouli,Panagiotis Marakos,Alexios-Leandros Skaltsounis,David A. Horne,Sangkil Nam,Katerina Gioti,Roxane Tenta

Research Article

s-Proline Covalented Silicapropyl Modified Magnetic Nanoparticles: Synthesis, Characterization, Biological and Catalytic Activity for the Synthesis of thiazolidin-4- ones

Journal: Current Organic Synthesis
Volume: 17 Issue: 6 Year: 2020 Page: 464-472
Author(s): Leila Zare Fekri

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