Search Result "Pim Inhibitors"


Review Article

Abnormal Signal Transduction via Over-expression of Pim-1 Regulated Senescence, Cell Cycle, Apoptosis and Metastatic Invasion: Novel Anticancer Targets and Their Potent Inhibitors from Marine Sources

Journal: Current Signal Transduction Therapy
Volume: 15 Issue: 1 Year: 2020 Page: 3-11
Author(s): Ankita Sharma,Sisir Nandi

Research Article

Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1711-1728
Author(s): Mahmoud A. Abdelaziz Mahmoud,Rafat Milad Mohareb,Mashari A. Al-Sharif

Research Article

Synthesis of Tetrahydrobenzo[b]thiophene-3-carbohydrazide Derivatives as Potential Anti-cancer Agents and Pim-1 Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2019 Page: 1737-1753
Author(s): Rafat Milad Mohareb,Wagnat Wahba Wardakhan,Nermeen Saeed Abbas

Research Article

Design, Synthesis, Molecular Docking, and Biological Studies of New Heterocyclic Compounds Derived from β-Diketones as Novel EGFR and Pim-1 Inhibitors Endowed with AntitumorActivity

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 22 Issue: 1 Year: 2022 Page: 2558-2576
Author(s): Rafat Milad Mohareb,Noha M. Asaad Bagato,Ibrahim Taha Radwan

Research Article

The Uses of Dimedone for the Synthesis of Thiophene, Thiazole and Annulated Derivatives with Antitumor, Pim-1 Kinase Inhibitions, PAINS Evaluations and Molecular Docking

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-20
Author(s): Wagnat W. Wardakhan,Amira M. Elmetwally,Abeer A. Mohamed,Rafat M. Mohareb

Research Article

New Approaches for the Uses of Cyclohexan-1,4-dione for the Synthesis of 5,6,7,8- tetrahydrobenzo[4,5]thieno[2,3-b]pyridine Derivatives used as Potential Anti-prostate Cancer Agents and Pim-1 Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1736-1749
Author(s): Rafat M. Mohareb,Nadia Y. Megally Abdo,Karam A. EL-Sharkawy

ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1340-1351
Author(s): S. Sarno, E. Papinutto, C. Franchin, J. Bain, M. Elliott, F. Meggio, Z. Kazimierczuk, A. Orzeszko, G. Zanotti, R. Battistutta, L. A. Pinna

Research Article

Potentially Inappropriate Medication Use in Older People: A CrosssectionalStudy Using Beers Criteria

Journal: Current Drug Safety
Volume: 17 Issue: 2 Year: 2022 Page: 121-128
Author(s): Ayse Nilufer Ozaydin,Fuat Nihat Ozaydin,Gülsüm Hatice Yüksel

Research Article

New Approaches for the Synthesis of Heterocyclic Compounds Corporating Benzo[d]imidazole as Anticancer Agents, Tyrosine, Pim-1 Kinases Inhibitions and their PAINS Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 3 Year: 2021 Page: 279-294
Author(s): Rafat M. Mohareb,Yara R. Milad,Bahaa M. Mostafa,Reem A. El-Ansary

Research Article

Synthesis of Thiazole, Thiophene, Pyran and Pyridine Derivatives Derived from 3-phenyl-1H-pyrazol-5(4H)-one with Anti-proliferative, Tyrosine Kinase and PIM-1 Kinase Inhibitions

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 4 Year: 2020 Page: 484-500
Author(s): Rafat Milad Mohareb,Ibram Refat Mikhail

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