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The Protein-Protein Interaction-Mediated Inactivation of PTEN

Journal: Current Molecular Medicine
Volume: 14 Issue: 1 Year: 2014 Page: 22-33
Author(s): J. De Melo,L. He,D. Tang

Therapeutic Targeting of Cancers with Loss of PTEN Function

Journal: Current Drug Targets
Volume: 15 Issue: 1 Year: 2014 Page: 65-79
Author(s): Lloye M. Dillon,Todd W. Miller

miR-221/222 Confers Radioresistance in Glioblastoma Cells Through Activating Akt Independent of PTEN Status

Journal: Current Molecular Medicine
Volume: 14 Issue: 1 Year: 2014 Page: 185-195
Author(s): W. Li,F. Guo,P. Wang,S. Hong,C. Zhang

Modulation of Signaling Enhances the Efficacy of the Combination of Satraplatin and Erlotinib

Journal: Current Drug Targets
Volume: 15 Issue: 14 Year: 2014 Page: 1312-1321
Author(s): Abolfazl Avan,Auke D. Adema,Eveline K. Hoebe,Charlotte M. Huijts,Amir Avan,Gareth J. Veal,Rob Ruijtenbeek,Katja Wosikowski,Godefridus J. Peters

Activation of PI3K/Akt/mTOR Pathway and Dual Inhibitors of PI3K and mTOR in Endometrial Cancer

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 26 Year: 2014 Page: 3070-3080
Author(s): Jiezhong Chen,Kong-Nan Zhao,Rui Li,Renfu Shao,Chen Chen

Targeting Drug-Resistant Prostate Cancer with Dual PI3K/mTOR Inhibition

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 26 Year: 2014 Page: 3048-3056
Author(s): K.D. Tang,Ming-Tat Ling

The Emerging Role of NRAS Mutations in Colorectal Cancer Patients Selected for Anti-EGFR Therapies

Journal: Reviews on Recent Clinical Trials
Volume: 9 Issue: 1 Year: 2014 Page: 8-12
Author(s): Fausto Meriggi,William Vermi,Paola Bertocchi,Alberto Zaniboni

Computational Medicinal Chemistry to Design Novel Phosphoinositide 3- Kinase (PI3K) Alpha Inhibitors in View of Cancer

Journal: Current Bioactive Compounds
Volume: 10 Issue: 3 Year: 2014 Page: 147-157
Author(s): Lorane I. Hage-Melim,Cleydson B.R. Santos,Joao G. Poiani,Miguel de Menezes Vaidergom,Eduardo S. Manzolli,Carlos H.T. de Paula da Silva

Research Article

Inhibition of Autophagy Strengthens Celastrol-Induced Apoptosis in Human Pancreatic Cancer In Vitro and In Vivo Models

Journal: Current Molecular Medicine
Volume: 14 Issue: 4 Year: 2014 Page: 555-563
Author(s): X. Zhao,S. Gao,H. Ren,H. Huang,W. Ji,J. Hao

Signaling Intermediates (MAPK and PI3K) as Therapeutic Targets in NSCLC

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 24 Year: 2014 Page: 3944-3957
Author(s): Ludovica Ciuffreda,Ursula Cesta Incani,Linda S. Steelman,Stephen L. Abrams,Italia Falcone,Anais Del Curatolo,William H. Chappell,Richard A. Franklin,Sabrina Vari,Francesco Cognetti,James A. McCubrey,Michele Milella

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