Search Result "PI3K�� inhibitors"


Dual Inhibitors of PI3K/mTOR or mTOR-Selective Inhibitors: Which Way Shall We Go?

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 3 Year: 2011 Page: 5528-5544
Author(s): D. A. Sabbah, M. G. Brattain, H. Zhong

Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2686-2714
Author(s): S. J. Shuttleworth, F. A. Silva, A. R.L. Cecil, C. D. Tomassi, T. J. Hill, F. I. Raynaud, P. A. Clarke, P. Workman

Present and Future of PI3K Pathway Inhibition in Cancer: Perspectives and Limitations

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2674-2685
Author(s): E. Ciraolo, F. Morello, E. Hirsch

Recent Developments in Anti-Cancer Agents Targeting PI3K, Akt and mTORC1/2

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 6 Issue: 2 Year: 2011 Page: 210-236
Author(s): Rodrigo Dienstmann, Jordi Rodon, Ben Markman, Josep Tabernero

ATP-Competitive Inhibitors of mTOR: An Update

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 2 Year: 2011 Page: 2995-3014
Author(s): S. Schenone, C. Brullo, F. Musumeci, M. Radi, M. Botta

Promising Activity of Mammalian Target of Rapamycin Inhibitors in Hematologic Malignancies Therapy

Journal: Current Signal Transduction Therapy
Volume: 6 Issue: 1 Year: 2011 Page: 44-54
Author(s): Ota Fuchs

Insulin Decreases Therapeutic Efficacy in Colon Cancer Cell Line HT29 Via the Activation of the PI3K/Akt Pathway

Journal: Current Drug Discovery Technologies
Volume: 8 Issue: 2 Year: 2011 Page: 119-125
Author(s): Jiezhong Chen, Andrew Katsifis, Changhua Hu, Xu-Feng Huang

Phosphatidylinositol 3-Kinase Isoforms as Novel Drug Targets

Journal: Current Drug Targets
Volume: 12 Issue: 7 Year: 2011 Page: 1056-1081
Author(s): Karolina Blajecka, Anna Borgstrom, Alexandre Arcaro

Development of Focal Adhesion Kinase Inhibitors in Cancer Therapy

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 11 Issue: 7 Year: 2011 Page: 638-642
Author(s): Wen Wee Ma

Targeting PDK1 in Cancer

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2763-2769
Author(s): C. Raimondi, M. Falasca

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