Search Result "PBPK models"


Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption

Journal: Current Drug Metabolism
Volume: 14 Issue: 1 Year: 2013 Page: 57-79
Author(s): Edwin C.Y. Chow,K. Sandy Pang

General Theory for Multiple Input-Output Perturbations in Complex Molecular Systems. 1. Linear QSPR Electronegativity Models in Physical, Organic, and Medicinal Chemistry

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 1713-1741
Author(s): Humberto Gonzalez-Diaz, Sonia Arrasate, Asier Gomez-SanJuan, Nuria Sotomayor, Esther Lete, Lina Besada-Porto, Juan M. Ruso

In Vitro Methods to Study the Interplay of Drug Metabolism and Efflux in the Intestine

Journal: Current Drug Metabolism
Volume: 14 Issue: 1 Year: 2013 Page: 102-111
Author(s): Sanna Siissalo,Aki T. Heikkinen

Quantitative Prediction of Glucuronidation in Humans Using the In Vitro- In Vivo Extrapolation Approach

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 11 Year: 2013 Page: 1343-1352
Author(s): Baojian Wu,Dong Dong,Ming Hu,Shuxing Zhang

Insight into Tissue Unbound Concentration: Utility in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 14 Issue: 3 Year: 2013 Page: 324-340
Author(s): T. Thanga Mariappan,Sandhya Mandlekar,Punit Marathe

Exhaled Breath Biomonitoring Using Laser Spectroscopy

Journal: Current Analytical Chemistry
Volume: 9 Issue: 3 Year: 2013 Page: 463-475
Author(s): Olavi Vaittinen, Florian Manfred Schmidt, Markus Metsala, Lauri Halonen

Co-Drug Strategy for Promoting Skin Targeting and Minimizing the Transdermal Diffusion of Hydroquinone and Tranexamic Acid

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 3 Year: 2013 Page: 4080-4092
Author(s): Pei-Wen Hsieh, Wei-Yu Chen, Ibrahim. A. Aljuffali, Chun-Che Chen, Jia-You Fang

Intestinal Targeting of Drugs: Rational Design Approaches and Challenges

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 776-802
Author(s): Kevin J. Filipski, Manthena V. Varma, Ayman F. El-Kattan, Catherine M. Ambler, Roger B. Ruggeri, Theunis C. Goosen, Kimberly O. Cameron

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