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PBPK Modeling of Intestinal and Liver Enzymes and Transporters in Drug Absorption and Sequential Metabolism

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 743-761
Author(s): Jianghong Fan, Shu Chen, Edwin C.Y. Chow, K. Sandy Pang

Integration of Physicochemical and Pharmacokinetic Parameters in Lead Optimization: A Physiological Pharmacokinetic Model Based Approach

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 143-153
Author(s): Elizabeth Hong-Geller, Sofiya N. Micheva-Viteva, Biju Benjamin, Tarani Kanta Barman, Tridib Chaira, Jyoti K. Paliwal

Application of Human Laboratory Models to Pharmacotherapy Development for Alcohol Dependence

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 1 Year: 2010 Page: 2149-2158
Author(s): Lara A. Ray, Kent E. Hutchison, Molly Tartter

Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 716-729
Author(s): A. S. Darwich, S. Neuhoff, M. Jamei, A. Rostami-Hodjegan

Editorial [Hot topic: Role of Intestinal Transporters and Metabolism in the Oral Absorption of Drugs and Prodrugs (Guest Editor: Manthena V. Varma)]

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 715-715
Author(s): Manthena Varma

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 762-777
Author(s): Tatsuhiko Tachibana, Motohiro Kato, Junichi Takano, Yuichi Sugiyama

Targeting Intestinal Transporters for Optimizing Oral Drug Absorption

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 730-742
Author(s): Manthena V. Varma, Catherine M. Ambler, Mohammad Ullah, Charles J. Rotter, Hao Sun, John Litchfield, Katherine S. Fenner, Ayman F. El-Kattan

CYP Inhibition-Mediated Drug-Drug Interactions

Journal: Current Enzyme Inhibition
Volume: 6 Issue: 3 Year: 2010 Page: 130-145
Author(s): Karoly Tihanyi, Monika L. Bakk, Eva Hellinger, Monika Vastag

Population Pharmacokinetic Evaluation of a Fully Human IgG2 Monoclonal Antibody in Patients with Inflammatory Diseases

Journal: Inflammation & Allergy - Drug Targets (Discontinued)
Volume: 9 Issue: 4 Year: 2010 Page: 229-237
Author(s): Mohammad Tabrizi, Bing Wang, Hong Lu, Saling Huang, Gregory Bell, Gisela Schwab, Lorin Roskos