Search Result "P-gp."


A Transcellular Assay to Assess the P-gp Inhibition in Early Stage of Drug Development

Journal: Drug Metabolism Letters
Volume: 6 Issue: 4 Year: 2012 Page: 285-291
Author(s): Jan-Shiang Taur, Edgar L. Schuck, Nancy Y. Wong

Three Decades of P-gp Inhibitors: Skimming Through Several Generations and Scaffolds

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 13 Year: 2012 Page: 1946-2025
Author(s): A. Palmeira,E. Sousa,M. H. Vasconcelos,M. M. Pinto

A Simplified Protocol Employing Elacridar in Rodents: A Screening Model in Drug Discovery to Assess P-gp Mediated Efflux at the Blood Brain Barrier

Journal: Drug Metabolism Letters
Volume: 6 Issue: 2 Year: 2012 Page: 134-144
Author(s): Rajareddy Kallem,Chetan P. Kulkarni,Dakshay Patel,Megha Thakur,Michael Sinz,Sheelendra P. Singh,S. Shahe Mahammad,Sandhya Mandlekar

Loxapine P-glycoprotein Interactions In Vitro

Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 26-32
Author(s): Andrea Reed, Keith Huie, Elke S. Perloff, James V. Cassella, Lori H. Takahashi

Structure and Ligand-based Design of P-glycoprotein Inhibitors: A Historical Perspective

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 27 Year: 2012 Page: 4197-4214
Author(s): Andreia Palmeira,Emilia Sousa,M. Helena Vasconcelos,Madalena Pinto,Miguel X. Fernandes

Colon Adenocarcinoma Multidrug Resistance Reverted by Euphorbia Diterpenes: Structure-Activity Relationships and Pharmacophore Modeling

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 9 Year: 2012 Page: 1015-1024
Author(s): Mariana Reis,Ricardo J. Ferreira,Julianna Serly,Noelia Duarte,Ana M. Madureira,Daniel J. V. A. Santos,Joseph Molnar,Maria-Jose U. Ferreira

Growth Inhibition of Human Non-Small Lung Cancer Cells H460 By Green Tea and Ginger Polyphenols

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 4 Year: 2012 Page: 383-390
Author(s): Mohamed Hessien,Saad El-Gendy,Thoria Donia,Morsy Abou Sikkena

Design, Synthesis and Multidrug Resistance Reversal Activity Evaluation of 8-Oxocoptisine Derivatives

Journal: Medicinal Chemistry
Volume: 8 Issue: 4 Year: 2012 Page: 742-748
Author(s): Jian Bo Wu,Fan Lei,Xiang Juan Cui,Yun He,Li Hai,Juan Zhang,Yong Wu

Renal and Hepatic Kinetics of Tc-99m-labelled Hexakis-methoxy-isobutyl Isonitrile

Journal: Drug Metabolism Letters
Volume: 6 Issue: 4 Year: 2012 Page: 242-246
Author(s): Sabina Dizdarevic, Mark Aplin, Nicola Ryan, Stephen G. Holt, Lawrence Goldberg, Kenneth A. Miles, A. Michael Peters

Herb-Drug Interactions and Mechanistic and Clinical Considerations

Journal: Current Drug Metabolism
Volume: 13 Issue: 5 Year: 2012 Page: 640-651
Author(s): Xiao-Wu Chen,Kevin B. Sneed,Si-Yuan Pan,Chuanhai Cao,Jagat R. Kanwar,Helen Chew,Shu- Feng Zhou

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